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Xxylt1 xyloside xylosyltransferase 1 [ Mus musculus (house mouse) ]

Gene ID: 268880, updated on 27-May-2024

Summary

Official Symbol
Xxylt1provided by MGI
Official Full Name
xyloside xylosyltransferase 1provided by MGI
Primary source
MGI:MGI:2146443
See related
Ensembl:ENSMUSG00000047434 AllianceGenome:MGI:2146443
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables UDP-xylosyltransferase activity and manganese ion binding activity. Involved in O-glycan processing. Predicted to be integral component of endoplasmic reticulum membrane. Orthologous to human XXYLT1 (xyloside xylosyltransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in adrenal adult (RPKM 12.5), ovary adult (RPKM 12.2) and 28 other tissues See more
Orthologs
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Genomic context

See Xxylt1 in Genome Data Viewer
Location:
16 B2; 16 21.34 cM
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (30774165..30900250, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (30955347..31081432, complement)

Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_40599 Neighboring gene predicted gene, 25375 Neighboring gene predicted gene, 46565 Neighboring gene STARR-seq mESC enhancer starr_40600 Neighboring gene STARR-seq mESC enhancer starr_40602 Neighboring gene STARR-positive B cell enhancer ABC_E10899 Neighboring gene predicted gene 15742 Neighboring gene predicted gene, 41440 Neighboring gene STARR-positive B cell enhancer ABC_E7437 Neighboring gene STARR-positive B cell enhancer ABC_E11610 Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:31081520-31081703 Neighboring gene predicted gene, 46554 Neighboring gene ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 Neighboring gene zinc finger protein 161 pseudogene Neighboring gene STARR-seq mESC enhancer starr_40608 Neighboring gene STARR-positive B cell enhancer ABC_E4163 Neighboring gene STARR-positive B cell enhancer ABC_E7438 Neighboring gene predicted gene, 52237 Neighboring gene predicted gene, 41442

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC19367

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables UDP-xylosyltransferase activity IDA
Inferred from Direct Assay
more info
PubMed 
enables UDP-xylosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 
enables magnesium ion binding ISO
Inferred from Sequence Orthology
more info
 
enables manganese ion binding IDA
Inferred from Direct Assay
more info
PubMed 
enables manganese ion binding ISO
Inferred from Sequence Orthology
more info
 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
enables transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables xylosyl alpha-1,3-xylosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables xylosyl alpha-1,3-xylosyltransferase activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in O-glycan processing IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in O-glycan processing IDA
Inferred from Direct Assay
more info
PubMed 
involved_in O-glycan processing ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
is_active_in endoplasmic reticulum membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in endoplasmic reticulum membrane ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
xyloside xylosyltransferase 1
Names
UDP-xylose:alpha-xyloside alpha-1,3-xylosyltransferase
NP_941028.2
XP_006522263.1
XP_030104996.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_198626.3NP_941028.2  xyloside xylosyltransferase 1

    See identical proteins and their annotated locations for NP_941028.2

    Status: VALIDATED

    Source sequence(s)
    AC090430, AC126280
    Consensus CDS
    CCDS49822.1
    UniProtKB/Swiss-Prot
    E9QL73, Q3TLX5, Q3U4G3, Q8K2I0
    Related
    ENSMUSP00000050246.8, ENSMUST00000055389.9
    Conserved Domains (2) summary
    COG1442
    Location:216352
    RfaJ; Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis]
    cl11394
    Location:117382
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000082.7 Reference GRCm39 C57BL/6J

    Range
    30774165..30900250 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030249136.2XP_030104996.1  xyloside xylosyltransferase 1 isoform X1

    Conserved Domains (1) summary
    cl11394
    Location:9196
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold
  2. XM_006522200.2XP_006522263.1  xyloside xylosyltransferase 1 isoform X1

    Conserved Domains (1) summary
    cl11394
    Location:9196
    Glyco_tranf_GTA_type; Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold