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GGT3P gamma-glutamyltransferase 3 pseudogene [ Homo sapiens (human) ]

Gene ID: 2679, updated on 23-Nov-2023

Summary

Official Symbol
GGT3Pprovided by HGNC
Official Full Name
gamma-glutamyltransferase 3 pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:4252
See related
Ensembl:ENSG00000197421 AllianceGenome:HGNC:4252
Gene type
pseudo
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
GGT3
Summary
Predicted to enable glutathione hydrolase activity and peptidyltransferase activity. Predicted to be involved in several processes, including peptide metabolic process; response to estradiol; and response to tumor necrosis factor. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in kidney (RPKM 10.5), small intestine (RPKM 4.5) and 12 other tissues See more
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Genomic context

See GGT3P in Genome Data Viewer
Location:
22q11.21
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 22 NC_000022.11 (18773689..18791961, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 22 NC_060946.1 (19147114..19165401, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (18761202..18779474, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene OCT4 hESC enhancer GRCh37_chr22:18721144-18721645 Neighboring gene family with sequence similarity 230 member E Neighboring gene family with sequence similarity 247 member C Neighboring gene OCT4-NANOG hESC enhancer GRCh37_chr22:18784852-18785463 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:18790287-18790788 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:18790789-18791288 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18808119-18808632 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18808633-18809148 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18809149-18809662 Neighboring gene OCT4-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18809663-18810176 Neighboring gene OCT4-H3K4me1 hESC enhancer GRCh37_chr22:18810177-18810690 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr22:18811010-18811514 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr22:18812019-18812522 Neighboring gene E2F transcription factor 6 pseudogene 1 Neighboring gene POM121 transmembrane nucleoporin pseudogene Neighboring gene POM121 transmembrane nucleoporin like 15, pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Other Names

  • inactive gamma-glutamyltranspeptidase 2

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables glutathione hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables leukotriene C4 gamma-glutamyl transferase activity IEA
Inferred from Electronic Annotation
more info
 
enables molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
involved_in biological_process ND
No biological Data available
more info
 
involved_in glutathione biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
involved_in glutathione catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in leukotriene D4 biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in peptide modification IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 
involved_in regulation of immune system process IBA
Inferred from Biological aspect of Ancestor
more info
 
involved_in regulation of inflammatory response IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
located_in extracellular exosome HDA PubMed 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_003267.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC008132
    Related
    ENST00000453783.2

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p14 Primary Assembly

    Range
    18773689..18791961 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060946.1 Alternate T2T-CHM13v2.0

    Range
    19147114..19165401 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)