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OR1J2 olfactory receptor family 1 subfamily J member 2 [ Homo sapiens (human) ]

Gene ID: 26740, updated on 22-Sep-2022

Summary

Official Symbol
OR1J2provided by HGNC
Official Full Name
olfactory receptor family 1 subfamily J member 2provided by HGNC
Primary source
HGNC:HGNC:8209
See related
Ensembl:ENSG00000197233 AllianceGenome:HGNC:8209
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HSA5; HG152; OR1J3; OR1J5; OR9-19; OST044
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OR1J2 in Genome Data Viewer
Location:
9q33.2
Exon count:
12
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (122447433..122580427)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (134708249..134709190)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (125273081..125274022)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene prostaglandin-endoperoxide synthase 1 Neighboring gene uncharacterized LOC124902264 Neighboring gene olfactory receptor family 1 subfamily J member 1 Neighboring gene olfactory receptor family 1 subfamily J member 4 Neighboring gene olfactory receptor family 1 subfamily N member 1 Neighboring gene olfactory receptor family 1 subfamily L member 8 Neighboring gene olfactory receptor family 1 subfamily N member 2 Neighboring gene uncharacterized LOC124902265 Neighboring gene olfactory receptor family 1 subfamily H member 1 pseudogene Neighboring gene olfactory receptor family 1 subfamily Q member 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

General gene information

Markers

Homology

Clone Names

  • FLJ16828

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
involved_in detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
involved_in signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
olfactory receptor 1J2
Names
HTPCRX15
olfactory receptor 1J3
olfactory receptor 1J5
olfactory receptor OR9-19
olfactory receptor, family 1, subfamily J, member 3
olfactory receptor, family 1, subfamily J, member 5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_054107.1NP_473448.1  olfactory receptor 1J2

    See identical proteins and their annotated locations for NP_473448.1

    Status: PROVISIONAL

    Source sequence(s)
    AL359636
    Consensus CDS
    CCDS35121.1
    UniProtKB/Swiss-Prot
    Q8NGS2, Q9NZP1
    UniProtKB/TrEMBL
    A0A126GW18
    Related
    ENSP00000335575.5, ENST00000335302.5
    Conserved Domains (1) summary
    cd15918
    Location:26294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    122447433..122580427
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024447517.2XP_024303285.1  olfactory receptor 1J2 isoform X1

    UniProtKB/Swiss-Prot
    Q9NZP1
    UniProtKB/TrEMBL
    A0A126GW18
    Conserved Domains (1) summary
    cd15918
    Location:26294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors
  2. XM_024447516.2XP_024303284.1  olfactory receptor 1J2 isoform X1

    UniProtKB/Swiss-Prot
    Q9NZP1
    UniProtKB/TrEMBL
    A0A126GW18
    Conserved Domains (1) summary
    cd15918
    Location:26294
    7tmA_OR1_7-like; olfactory receptor families 1, 7, and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RNA

  1. XR_007061274.1 RNA Sequence

  2. XR_007061272.1 RNA Sequence

  3. XR_007061273.1 RNA Sequence

  4. XR_007061276.1 RNA Sequence

  5. XR_007061275.1 RNA Sequence

  6. XR_007061271.1 RNA Sequence

  7. XR_007061277.1 RNA Sequence

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    134708249..134709190
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)