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OR4F3 olfactory receptor family 4 subfamily F member 3 [ Homo sapiens (human) ]

Gene ID: 26683, updated on 11-Jun-2021

Summary

Official Symbol
OR4F3provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily F member 3provided by HGNC
Primary source
HGNC:HGNC:8300
See related
Ensembl:ENSG00000230178
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OR4F3 in Genome Data Viewer
Location:
5q35.3
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (181342142..181370030)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (180769143..180797031)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100132062 Neighboring gene septin 14 pseudogene 5 Neighboring gene capicua transcriptional repressor pseudogene 15 Neighboring gene WBP1L pseudogene 4 Neighboring gene ribosomal protein L23a pseudogene 45

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 4F3/4F16/4F29
Names
olfactory receptor OR1-1
olfactory receptor OR7-21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005224.2NP_001005224.1  olfactory receptor 4F3/4F16/4F29

    See identical proteins and their annotated locations for NP_001005224.1

    Status: VALIDATED

    Source sequence(s)
    AC138030, AC138035
    Consensus CDS
    CCDS43415.1
    UniProtKB/Swiss-Prot
    Q6IEY1
    UniProtKB/TrEMBL
    A0A126GV92
    Related
    ENSP00000394282.1, ENST00000456475.1
    Conserved Domains (1) summary
    cd15226
    Location:35291
    7tmA_OR4-like; olfactory receptor family 4 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    181342142..181370030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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