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OR10H1 olfactory receptor family 10 subfamily H member 1 [ Homo sapiens (human) ]

Gene ID: 26539, updated on 5-Mar-2024


Official Symbol
OR10H1provided by HGNC
Official Full Name
olfactory receptor family 10 subfamily H member 1provided by HGNC
Primary source
See related
Ensembl:ENSG00000186723 AllianceGenome:HGNC:8172
Gene type
protein coding
RefSeq status
Homo sapiens
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Low expression observed in reference dataset See more
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Genomic context

Exon count:
Annotation release Status Assembly Chr Location
RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (15804549..15815664, complement)
RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (15932396..15943489, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (15915359..15926474, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene cytochrome P450 family 4 subfamily F member 24, pseudogene Neighboring gene olfactory receptor family 10 subfamily H member 5 Neighboring gene zinc finger protein 861, pseudogene Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr19:15939001-15940200 Neighboring gene collagen alpha-1(I) chain-like Neighboring gene CDK7 strongly-dependent group 2 enhancer GRCh37_chr19:15945748-15946947 Neighboring gene urothelial cancer associated 1

Genomic regions, transcripts, and products


  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Pathways from PubChem


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
involved_in detection of chemical stimulus involved in sensory perception of smell IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info

General protein information

Preferred Names
olfactory receptor 10H1
olfactory receptor OR19-27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_013940.4NP_039228.1  olfactory receptor 10H1

    See identical proteins and their annotated locations for NP_039228.1

    Status: VALIDATED

    Source sequence(s)
    Consensus CDS
    Q6IFQ2, Q96R59, Q9Y4A9
    A0A126GVU5, A0A126GWG6
    ENSP00000493436.1, ENST00000641419.1
    Conserved Domains (1) summary
    7tmA_OR10A-like; olfactory receptor subfamily 10A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly


  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    15804549..15815664 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0


  1. NC_060943.1 Alternate T2T-CHM13v2.0

    15932396..15943489 complement
    GenBank, FASTA, Sequence Viewer (Graphics)