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Ciao1 cytosolic iron-sulfur protein assembly 1 [ Mus musculus (house mouse) ]

Gene ID: 26371, updated on 19-Jun-2024


Official Symbol
Ciao1provided by MGI
Official Full Name
cytosolic iron-sulfur protein assembly 1provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000003662 AllianceGenome:MGI:1346998
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to enable DNA-binding transcription factor activity. Predicted to be involved in iron-sulfur cluster assembly and protein maturation by iron-sulfur cluster transfer. Predicted to act upstream of or within regulation of transcription by RNA polymerase II. Predicted to be located in cytoplasm. Predicted to be part of CIA complex and MMXD complex. Is expressed in several structures, including central nervous system; genitourinary system; liver; neural retina; and skin. Orthologous to human CIAO1 (cytosolic iron-sulfur assembly component 1). [provided by Alliance of Genome Resources, Apr 2022]
Ubiquitous expression in kidney adult (RPKM 12.0), cerebellum adult (RPKM 10.9) and 28 other tissues See more
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Genomic context

See Ciao1 in Genome Data Viewer
2 F1; 2 61.86 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (127082858..127089736, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (127240938..127247816, complement)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810024B03 gene Neighboring gene STARR-positive B cell enhancer ABC_E3401 Neighboring gene small nuclear ribonucleoprotein 200 (U5) Neighboring gene STARR-positive B cell enhancer ABC_E642 Neighboring gene transmembrane protein 127 Neighboring gene STARR-positive B cell enhancer mm9_chr2:127095727-127096028 Neighboring gene StAR related lipid transfer domain containing 7

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a


Products Interactant Other Gene Complex Source Pubs Description

General protein information

Preferred Names
probable cytosolic iron-sulfur protein assembly protein CIAO1
WD repeat domain 39
WD repeat-containing protein 39
WD40 protein Ciao1
cytosolic iron-sulfur protein assembly 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_025296.4NP_079572.2  probable cytosolic iron-sulfur protein assembly protein CIAO1

    See identical proteins and their annotated locations for NP_079572.2

    Status: VALIDATED

    Source sequence(s)
    AK028376, BI734652, BU555826
    Consensus CDS
    Q99KN2, Q9DCZ7
    ENSMUSP00000003759.5, ENSMUST00000003759.11
    Conserved Domains (2) summary
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    7WD40; WD40 repeat [structural motif]

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000068.8 Reference GRCm39 C57BL/6J

    127082858..127089736 complement
    GenBank, FASTA, Sequence Viewer (Graphics)