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OR5H1 olfactory receptor family 5 subfamily H member 1 [ Homo sapiens (human) ]

Gene ID: 26341, updated on 25-Aug-2020

Summary

Official Symbol
OR5H1provided by HGNC
Official Full Name
olfactory receptor family 5 subfamily H member 1provided by HGNC
Primary source
HGNC:HGNC:8346
See related
Ensembl:ENSG00000231192
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HTPCRX14; HSHTPCRX14
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs

Genomic context

See OR5H1 in Genome Data Viewer
Location:
3q11.2
Exon count:
2
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 3 NC_000003.12 (98130721..98138548)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (97851542..97852483)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily AC member 4 pseudogene Neighboring gene POU class 5 homeobox 1 pseudogene 7 Neighboring gene uncharacterized LOC105373996 Neighboring gene olfactory receptor family 5 subfamily H member 14 Neighboring gene olfactory receptor family 5 subfamily H member 15

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 
detection of chemical stimulus involved in sensory perception of smell IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
plasma membrane TAS
Traceable Author Statement
more info
 

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005338.2NP_001005338.1  olfactory receptor 5H1

    See identical proteins and their annotated locations for NP_001005338.1

    Status: VALIDATED

    Source sequence(s)
    AC117460
    Consensus CDS
    CCDS33797.1
    UniProtKB/Swiss-Prot
    A6NKK0
    UniProtKB/TrEMBL
    A0A126GW79
    Related
    ENSP00000492953.1, ENST00000641874.1
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31305
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p13 Primary Assembly

    Range
    98130721..98138548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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