U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

OR5K1 olfactory receptor family 5 subfamily K member 1 [ Homo sapiens (human) ]

Gene ID: 26339, updated on 22-Sep-2022

Summary

Official Symbol
OR5K1provided by HGNC
Official Full Name
olfactory receptor family 5 subfamily K member 1provided by HGNC
Primary source
HGNC:HGNC:8349
See related
Ensembl:ENSG00000232382 AllianceGenome:HGNC:8349
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR3-8; HTPCRX10; HSHTPCRX10
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See OR5K1 in Genome Data Viewer
Location:
3q11.2
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 3 NC_000003.12 (98463201..98472924)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 3 NC_060927.1 (101166890..101176614)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 3 NC_000003.11 (98182045..98191768)

Chromosome 3 - NC_000003.12Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 5 subfamily K member 3 Neighboring gene ubiquitin family domain containing 1 pseudogene 1 Neighboring gene olfactory receptor family 5 subfamily K member 2 Neighboring gene claudin domain containing 1

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 5K1
Names
olfactory receptor OR3-8

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_042151.1 RefSeqGene

    Range
    5001..6097
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001004736.4NP_001004736.2  olfactory receptor 5K1

    See identical proteins and their annotated locations for NP_001004736.2

    Status: REVIEWED

    Source sequence(s)
    AC074274
    Consensus CDS
    CCDS43115.1
    UniProtKB/Swiss-Prot
    Q6IF46, Q8NHB7
    UniProtKB/TrEMBL
    A0A126GWC1
    Related
    ENSP00000493267.1, ENST00000642057.1
    Conserved Domains (2) summary
    pfam00001
    Location:41290
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31308
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000003.12 Reference GRCh38.p14 Primary Assembly

    Range
    98463201..98472924
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060927.1 Alternate T2T-CHM13v2.0

    Range
    101166890..101176614
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)