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OR2K2 olfactory receptor family 2 subfamily K member 2 [ Homo sapiens (human) ]

Gene ID: 26248, updated on 22-Sep-2022

Summary

Official Symbol
OR2K2provided by HGNC
Official Full Name
olfactory receptor family 2 subfamily K member 2provided by HGNC
Primary source
HGNC:HGNC:8264
See related
Ensembl:ENSG00000171133 AllianceGenome:HGNC:8264
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR2AN1P; OR2AR1P; HTPCRH06; HSHTPCRH06
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Expression
Low expression observed in reference dataset See more
Orthologs
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Genomic context

See OR2K2 in Genome Data Viewer
Location:
9q31.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 9 NC_000009.12 (111327229..111330224, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 9 NC_060933.1 (123498588..123501583, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (114089509..114092504, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376219 Neighboring gene VISTA enhancer hs1447 Neighboring gene microRNA 7702 Neighboring gene Ecm29 proteasome adaptor and scaffold Neighboring gene RNA, 5S ribosomal pseudogene 294 Neighboring gene zinc finger protein 483 Neighboring gene prostaglandin reductase 1

Genomic regions, transcripts, and products

Phenotypes

EBI GWAS Catalog

Description
Multiple loci are associated with white blood cell phenotypes.
EBI GWAS Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
EBI GWAS Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC133152

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
olfactory receptor 2K2
Names
olfactory receptor OR9-17
olfactory receptor, family 2, subfamily AN, member 1 pseudogene
olfactory receptor, family 2, subfamily AR, member 1 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_205859.2NP_995581.1  olfactory receptor 2K2

    See identical proteins and their annotated locations for NP_995581.1

    Status: VALIDATED

    Source sequence(s)
    AL354661
    Consensus CDS
    CCDS6778.1
    UniProtKB/Swiss-Prot
    Q6IFI5, Q8NGT1
    UniProtKB/TrEMBL
    A0A0C4DFP3
    Related
    ENSP00000305055.1, ENST00000302681.3
    Conserved Domains (1) summary
    cd15430
    Location:25293
    7tmA_OR13-like; olfactory receptor family 13 and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p14 Primary Assembly

    Range
    111327229..111330224 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060933.1 Alternate T2T-CHM13v2.0

    Range
    123498588..123501583 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)