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FBXL21P F-box and leucine rich repeat protein 21, pseudogene [ Homo sapiens (human) ]

Gene ID: 26223, updated on 23-Nov-2021

Summary

Official Symbol
FBXL21Pprovided by HGNC
Official Full Name
F-box and leucine rich repeat protein 21, pseudogeneprovided by HGNC
Primary source
HGNC:HGNC:13600
See related
MIM:609087
Gene type
pseudo
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FBL3B; Fbl21; FBXL21; FBXL3B; FBXL3P
Summary
This locus represents a transcribed pseudogene that is related to genes encoding members of the F-box family of proteins. [provided by RefSeq, Nov 2017]
Annotation information
Annotation category: suggests misassembly
Expression
Biased expression in prostate (RPKM 1.0), adrenal (RPKM 0.7) and 8 other tissues See more
Orthologs
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Genomic context

See FBXL21P in Genome Data Viewer
Location:
5q31.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 5 NC_000005.10 (135930297..135941996)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 5 NC_000005.9 (135265986..135277685)

Chromosome 5 - NC_000005.10Genomic Context describing neighboring genes Neighboring gene solute carrier family 25 member 48 Neighboring gene uncharacterized LOC107986453 Neighboring gene interleukin 9 Neighboring gene Sharpr-MPRA regulatory region 2274 Neighboring gene leukocyte cell derived chemotaxin 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Other Names

  • F-box and leucine-rich repeat protein 21
  • F-box and leucine-rich repeat protein 3 pseudogene
  • F-box and leucine-rich repeat protein 3B
  • F-box protein Fbl3b
  • F-box/LRR-repeat protein 21
  • F-box/LRR-repeat protein 3B

Clone Names

  • MGC120237

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables ubiquitin-protein transferase activity NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
involved_in G2/M transition of mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in SCF-dependent proteasomal ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in entrainment of circadian clock by photoperiod IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in entrainment of circadian clock by photoperiod ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 
involved_in protein ubiquitination ISS
Inferred from Sequence or Structural Similarity
more info
 
involved_in protein ubiquitination NAS
Non-traceable Author Statement
more info
PubMed 
involved_in regulation of cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
involved_in rhythmic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
part_of SCF ubiquitin ligase complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
part_of SCF ubiquitin ligase complex ISS
Inferred from Sequence or Structural Similarity
more info
 
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in cytosol ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in cytosol TAS
Traceable Author Statement
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
part_of ubiquitin ligase complex NAS
Non-traceable Author Statement
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_152420.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC002428
  2. NR_152421.1 RNA Sequence

    Status: REVIEWED

    Source sequence(s)
    AC002428

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000005.10 Reference GRCh38.p13 Primary Assembly

    Range
    135930297..135941996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_012159.4: Suppressed sequence

    Description
    NM_012159.4: This RefSeq was removed because it is now thought that this gene is a pseudogene.
  2. NR_132347.1: Suppressed sequence

    Description
    NR_132347.1: This RefSeq was removed because currently there is not sufficient data to support this transcript.
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