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FGFR1OP2 FGFR1 oncogene partner 2 [ Homo sapiens (human) ]

Gene ID: 26127, updated on 3-Oct-2020

Summary

Official Symbol
FGFR1OP2provided by HGNC
Official Full Name
FGFR1 oncogene partner 2provided by HGNC
Primary source
HGNC:HGNC:23098
See related
Ensembl:ENSG00000111790 MIM:608858
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
WIT3.0; HSPC123-like
Expression
Ubiquitous expression in ovary (RPKM 23.0), adrenal (RPKM 22.0) and 25 other tissues See more
Orthologs

Genomic context

See FGFR1OP2 in Genome Data Viewer
Location:
12p11.23
Exon count:
7
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (26938470..26966648)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (27091305..27119581)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene inositol 1,4,5-trisphosphate receptor type 2 Neighboring gene uncharacterized LOC105369706 Neighboring gene enoyl-CoA hydratase domain containing 2 pseudogene Neighboring gene integrator complex subunit 13 Neighboring gene transmembrane 7 superfamily member 3 Neighboring gene mediator complex subunit 21 Neighboring gene chromosome 12 open reading frame 71

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ37569, DKFZp564O1863, DKFZp586C1423

Gene Ontology Provided by GOA

Function Evidence Code Pubs
identical protein binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
response to wounding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
wound healing IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
FGFR1 oncogene partner 2
Names
fibroblast growth factor receptor 1 oncogene partner 2
wound inducible transcript 3.0

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001171887.2NP_001165358.1  FGFR1 oncogene partner 2 isoform 2

    See identical proteins and their annotated locations for NP_001165358.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1.
    Source sequence(s)
    AC024896, BI829470, DA388639
    Consensus CDS
    CCDS53767.1
    UniProtKB/Swiss-Prot
    Q9NVK5
    Related
    ENSP00000323763.5, ENST00000327214.5
    Conserved Domains (1) summary
    pfam05769
    Location:2183
    DUF837; Protein of unknown function (DUF837)
  2. NM_001171888.2NP_001165359.1  FGFR1 oncogene partner 2 isoform 3

    See identical proteins and their annotated locations for NP_001165359.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 3' UTR and 3' coding region, compared to variant 1. It encodes isoform 3, which has a shorter and distinct C-terminus, compared to isoform 1.
    Source sequence(s)
    AC024896, AK001534, BC032143
    Consensus CDS
    CCDS53766.1
    UniProtKB/Swiss-Prot
    Q9NVK5
    Related
    ENSP00000437556.1, ENST00000546072.5
    Conserved Domains (1) summary
    pfam05769
    Location:2133
    DUF837; Protein of unknown function (DUF837)
  3. NM_015633.3NP_056448.1  FGFR1 oncogene partner 2 isoform 1

    See identical proteins and their annotated locations for NP_056448.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC024896, AK001534
    Consensus CDS
    CCDS8709.1
    UniProtKB/Swiss-Prot
    Q9NVK5
    Related
    ENSP00000229395.3, ENST00000229395.8
    Conserved Domains (1) summary
    pfam05769
    Location:2221
    SIKE; SIKE family

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    26938470..26966648
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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