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glr4197 hypothetical protein [ Gloeobacter violaceus PCC 7421 ]

Gene ID: 2602600, discontinued on 6-Mar-2020
  • This record was discontinued.

Summary

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Gene symbol
glr4197
Gene description
hypothetical protein
Locus tag
glr4197
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Gloeobacter violaceus PCC 7421 (strain: PCC 7421)
Lineage
Bacteria; Cyanobacteria; Gloeobacteria; Gloeobacterales; Gloeobacter
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Genomic regions, transcripts, and products

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Genomic Sequence:
NC_005125.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest that neurosteroids bind to two sites per GLIC subunit, both within the transmembrane domain; one site is an intrasubunit site, and the other is located in the interface between subunits. The neurosteroids ligands used in this study were derivatives of 3alpha-hydroxypregnane and tetrahydrodeoxycorticosterone.
    Title: Mapping two neurosteroid-modulatory sites in the prototypic pentameric ligand-gated ion channel GLIC.
  2. Here we delineate protein motions underlying Gloeobacter violaceus ligand-gated ion channel gating in a membrane environment and report the interface conformation in the closed and the desensitized states.
    Title: Structural basis for allosteric coupling at the membrane-protein interface in Gloeobacter violaceus ligand-gated ion channel (GLIC).
  3. X-ray structure of a bacterial ligand-gated ion channel with ketamine bound to an intersubunit cavity that partially overlaps with the homologous antagonist-binding site.
    Title: Structure of the pentameric ligand-gated ion channel GLIC bound with anesthetic ketamine.
  4. The overall findings show that His-235 in the transmembrane region of GLIC is a novel proton binding site linked to channel activation.
    Title: Intramembrane proton binding site linked to activation of bacterial pentameric ion channel.
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General protein information

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Names
hypothetical protein

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_005125.1 Reference assembly

    Range
    4393576..4394655
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_927143.1 hypothetical protein glr4197 [Gloeobacter violaceus PCC 7421]

    Status: REVIEWED

Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q7NDN8.1

Gene LinkOut

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Research Materials