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TAS2R20 taste 2 receptor member 20 [ Homo sapiens (human) ]

Gene ID: 259295, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R20provided by HGNC
Official Full Name
taste 2 receptor member 20provided by HGNC
Primary source
HGNC:HGNC:19109
See related
Ensembl:ENSG00000255837 MIM:613962; AllianceGenome:HGNC:19109
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R20; T2R49; T2R56; TAS2R49
Summary
This gene encodes a member of the taste receptor two family of class C G-protein coupled receptors. Receptors of this family have a short extracellular N-terminus, seven transmembrane helices, three extracellular loops and three intracellular loops, and an intracellular C-terminus. Members of this family are expressed in a subset of taste receptor cells, where they function in bitter taste reception, as well as in non-gustatory cells including those of the brain, reproductive organs, respiratory system, and gastrointestinal system. This gene maps to the taste receptor gene cluster on chromosome 12p13. [provided by RefSeq, Jul 2016]
Orthologs
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Genomic context

See TAS2R20 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (10995961..10998304, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 12 NC_060936.1 (10868982..10871325, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (11148560..11150903, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 15 pseudogene Neighboring gene taste 2 receptor member 50 Neighboring gene taste 2 receptor member 19 Neighboring gene taste 2 receptor member 31

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119118, MGC119119, MGC119120, MGC119121, MGC134637

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 20
Names
taste receptor type 2 member 56
taste receptor, type 2, member 49

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_051254.1 RefSeqGene

    Range
    5001..7344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_176889.4NP_795370.2  taste receptor type 2 member 20

    See identical proteins and their annotated locations for NP_795370.2

    Status: REVIEWED

    Source sequence(s)
    AC018630, BC100916, C20782, CD722569
    Consensus CDS
    CCDS8639.1
    UniProtKB/Swiss-Prot
    P59543, Q645X9
    Related
    ENSP00000441624.1, ENST00000538986.2
    Conserved Domains (1) summary
    cd15027
    Location:3294
    7tm_TAS2R43-like; mammalian taste receptor 2, subtype 43, and related proteins, member of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    10995961..10998304 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    194667..197010 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_2

Genomic

  1. NT_187658.1 Reference GRCh38.p14 ALT_REF_LOCI_2

    Range
    194656..196999 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060936.1 Alternate T2T-CHM13v2.0

    Range
    10868982..10871325 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)