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TAS2R31 taste 2 receptor member 31 [ Homo sapiens (human) ]

Gene ID: 259290, updated on 1-Jun-2020

Summary

Official Symbol
TAS2R31provided by HGNC
Official Full Name
taste 2 receptor member 31provided by HGNC
Primary source
HGNC:HGNC:19113
See related
Ensembl:ENSG00000256436 MIM:612669
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R31; T2R44; T2R53; TAS2R44
Summary
TAS2R44 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009]

Genomic context

See TAS2R31 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (11030387..11031407, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (11182986..11184006, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 20 Neighboring gene taste 2 receptor member 19 Neighboring gene taste 2 receptor member 63 pseudogene Neighboring gene taste 2 receptor member 46

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
bitter taste receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
integral component of membrane IC
Inferred by Curator
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 31
Names
taste receptor type 2 member 44
taste receptor type 2 member 53
taste receptor, type 2, member 31

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176885.2NP_795366.2  taste receptor type 2 member 31

    See identical proteins and their annotated locations for NP_795366.2

    Status: VALIDATED

    Source sequence(s)
    AC018630
    Consensus CDS
    CCDS53747.1
    UniProtKB/Swiss-Prot
    P59538
    Related
    ENSP00000375093.2, ENST00000390675.2
    Conserved Domains (1) summary
    cd15027
    Location:3294
    7tm_TAS2R43-like; mammalian taste receptor 2, subtype 43, and related proteins, member of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    11030387..11031407 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p13 ALT_REF_LOCI_1

    Range
    229093..230113 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p13 ALT_REF_LOCI_2

Genomic

  1. NT_187658.1 Reference GRCh38.p13 ALT_REF_LOCI_2

    Range
    229392..230412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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