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TAS2R43 taste 2 receptor member 43 [ Homo sapiens (human) ]

Gene ID: 259289, updated on 22-Sep-2022

Summary

Official Symbol
TAS2R43provided by HGNC
Official Full Name
taste 2 receptor member 43provided by HGNC
Primary source
HGNC:HGNC:18875
See related
Ensembl:ENSG00000255374 MIM:612668; AllianceGenome:HGNC:18875
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R43; T2R52
Summary
TAS2R43 belongs to the large TAS2R receptor family. TAS2Rs are expressed on the surface of taste receptor cells and mediate the perception of bitterness through a G protein-coupled second messenger pathway (Conte et al., 2002 [PubMed 12584440]). For further information on TAS2Rs, see MIM 604791.[supplied by OMIM, Mar 2009]
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Genomic context

See TAS2R43 in Genome Data Viewer
Location:
12p13.2
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 12 NC_000012.12 (11091287..11092313, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (11243886..11244912, complement)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene PRH1-PRR4 readthrough Neighboring gene proline rich protein HaeIII subfamily 1 Neighboring gene PRH1-TAS2R14 readthrough Neighboring gene taste 2 receptor member 46 Neighboring gene taste 2 receptor member 64 pseudogene Neighboring gene taste 2 receptor member 30 Neighboring gene taste 2 receptor member 18 pseudogene

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General protein information

Preferred Names
taste receptor type 2 member 43
Names
taste receptor type 2 member 52
taste receptor, type 2, member 43

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176884.2NP_795365.2  taste receptor type 2 member 43

    See identical proteins and their annotated locations for NP_795365.2

    Status: VALIDATED

    Source sequence(s)
    AC018630
    Consensus CDS
    CCDS53749.1
    UniProtKB/Swiss-Prot
    P59537, Q645X4
    Related
    ENSP00000431719.1, ENST00000531678.1
    Conserved Domains (1) summary
    pfam05296
    Location:1298
    TAS2R; Taste receptor protein (TAS2R)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p14 Primary Assembly

    Range
    11091287..11092313 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 ALT_REF_LOCI_1

Genomic

  1. NW_003571050.1 Reference GRCh38.p14 ALT_REF_LOCI_1

    Range
    290014..291040 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)