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TAS2R41 taste 2 receptor member 41 [ Homo sapiens (human) ]

Gene ID: 259287, updated on 13-May-2022

Summary

Official Symbol
TAS2R41provided by HGNC
Official Full Name
taste 2 receptor member 41provided by HGNC
Primary source
HGNC:HGNC:18883
See related
Ensembl:ENSG00000221855 MIM:613965; AllianceGenome:HGNC:18883
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
T2R41; T2R59
Summary
This gene encodes a member of the bitter taste receptor family which belong to the G protein-coupled receptor superfamily and are predominantly expressed in taste receptor cells of the tongue and palate epithelia. This intronless taste receptor gene encodes a seven-transmembrane receptor protein, functioning as a bitter taste receptor. This gene is clustered together with eight other taste receptor genes on chromosome 7. Chloramphenicol is an agonist for the encoded protein. [provided by RefSeq, Jul 2017]
Orthologs
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Genomic context

See TAS2R41 in Genome Data Viewer
Location:
7q35
Exon count:
1
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 7 NC_000007.14 (143477873..143478796)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 7 NC_060931.1 (144833246..144834169)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 7 NC_000007.13 (143174966..143175889)

Chromosome 7 - NC_000007.14Genomic Context describing neighboring genes Neighboring gene EPHA1 antisense RNA 1 Neighboring gene taste 2 receptor member 62 pseudogene Neighboring gene taste 2 receptor member 60 Neighboring gene Sharpr-MPRA regulatory region 6558 Neighboring gene olfactory receptor family 2 subfamily R member 1, pseudogene

Genomic regions, transcripts, and products

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119928, MGC119929

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
NOT enables bitter taste receptor activity IDA
Inferred from Direct Assay
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in integral component of membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
taste receptor type 2 member 41
Names
taste receptor type 2 member 59
taste receptor, type 2, member 41

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_176883.2NP_795364.2  taste receptor type 2 member 41

    See identical proteins and their annotated locations for NP_795364.2

    Status: REVIEWED

    Source sequence(s)
    AY114093
    Consensus CDS
    CCDS43663.1
    UniProtKB/Swiss-Prot
    P59536
    Related
    ENSP00000386201.1, ENST00000408916.1
    Conserved Domains (1) summary
    cd15018
    Location:20295
    7tm_TAS2R41-like; mammalian taste receptor 2, subtype 41, member of the seven-transmembrane G protein-coupled receptor superfamily

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000007.14 Reference GRCh38.p14 Primary Assembly

    Range
    143477873..143478796
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_018654714.1 Reference GRCh38.p14 PATCHES

    Range
    97237..98160
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060931.1 Alternate T2T-CHM13v2.0

    Range
    144833246..144834169
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)