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RPL36 ribosomal protein L36 [ Homo sapiens (human) ]

Gene ID: 25873, updated on 4-Oct-2020

Summary

Official Symbol
RPL36provided by HGNC
Official Full Name
ribosomal protein L36provided by HGNC
Primary source
HGNC:HGNC:13631
See related
Ensembl:ENSG00000130255 MIM:617893
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
L36
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L36E family of ribosomal proteins. It is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Expression
Ubiquitous expression in ovary (RPKM 642.4), adrenal (RPKM 277.3) and 25 other tissues See more
Orthologs

Genomic context

See RPL36 in Genome Data Viewer
Location:
19p13.3
Exon count:
3
Annotation release Status Assembly Chr Location
109.20200815 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (5690295..5691875)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (5690272..5691678)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene mitochondrial contact site and cristae organizing system subunit 13 Neighboring gene hydroxysteroid 11-beta dehydrogenase 1 like Neighboring gene lon peptidase 1, mitochondrial Neighboring gene cation channel sperm associated auxiliary subunit delta Neighboring gene proline rich 22

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • DKFZp566B023

Gene Ontology Provided by GOA

Function Evidence Code Pubs
RNA binding HDA PubMed 
structural constituent of ribosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
structural constituent of ribosome NAS
Non-traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
SRP-dependent cotranslational protein targeting to membrane TAS
Traceable Author Statement
more info
 
cytoplasmic translation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasmic translation IDA
Inferred from Direct Assay
more info
PubMed 
nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
Traceable Author Statement
more info
 
translation NAS
Non-traceable Author Statement
more info
PubMed 
translational initiation TAS
Traceable Author Statement
more info
 
viral transcription TAS
Traceable Author Statement
more info
 
Component Evidence Code Pubs
cytoplasm HDA PubMed 
cytosol TAS
Traceable Author Statement
more info
 
cytosolic large ribosomal subunit HDA PubMed 
cytosolic large ribosomal subunit IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosolic large ribosomal subunit IDA
Inferred from Direct Assay
more info
PubMed 
membrane HDA PubMed 
nucleolus HDA PubMed 
nucleolus IDA
Inferred from Direct Assay
more info
 
polysomal ribosome IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
60S ribosomal protein L36
Names
large ribosomal subunit protein eL36

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_017015.1 RefSeqGene

    Range
    5035..6615
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_015414.4NP_056229.2  60S ribosomal protein L36

    See identical proteins and their annotated locations for NP_056229.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has a different 5' UTR than variant 1. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC011499, BC003052, BM015858
    Consensus CDS
    CCDS12147.1
    UniProtKB/Swiss-Prot
    Q9Y3U8
    Related
    ENSP00000378081.2, ENST00000394580.2
    Conserved Domains (1) summary
    pfam01158
    Location:494
    Ribosomal_L36e; Ribosomal protein L36e
  2. NM_033643.3NP_378669.1  60S ribosomal protein L36

    See identical proteins and their annotated locations for NP_378669.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) is the predominant transcript and has a different 5' UTR than variant 2. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AC011499, BC004971, BM841746
    Consensus CDS
    CCDS12147.1
    UniProtKB/Swiss-Prot
    Q9Y3U8
    Related
    ENSP00000252543.3, ENST00000347512.8
    Conserved Domains (1) summary
    pfam01158
    Location:494
    Ribosomal_L36e; Ribosomal protein L36e

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20200815

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    5690295..5691875
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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