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TMEM184B transmembrane protein 184B [ Homo sapiens (human) ]

Gene ID: 25829, updated on 3-Jun-2018
Official Symbol
TMEM184Bprovided by HGNC
Official Full Name
transmembrane protein 184Bprovided by HGNC
Primary source
HGNC:HGNC:1310
See related
Ensembl:ENSG00000198792 Vega:OTTHUMG00000030557
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FM08; HS5O6A; C22orf5; HSPC256
Expression
Ubiquitous expression in placenta (RPKM 20.3), fat (RPKM 18.2) and 25 other tissues See more
Orthologs
See TMEM184B in Genome Data Viewer
Location:
22q13.1
Exon count:
13
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 22 NC_000022.11 (38219291..38273034, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 22 NC_000022.10 (38612415..38669040, complement)

Chromosome 22 - NC_000022.11Genomic Context describing neighboring genes Neighboring gene phospholipase A2 group VI Neighboring gene MAF bZIP transcription factor F Neighboring gene RNA, 7SL, cytoplasmic 704, pseudogene Neighboring gene small nucleolar RNA, H/ACA box 92 Neighboring gene TPTEP2-CSNK1E readthrough Neighboring gene casein kinase 1 epsilon Neighboring gene TPTE pseudogene 2

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

NHGRI GWAS Catalog

Description
Genome-wide association study identifies multiple loci associated with both mammographic density and breast cancer risk.
NHGRI GWA Catalog
Products Interactant Other Gene Complex Source Pubs Description

Markers

Homology

Clone Names

  • DKFZp586A1024, DKFZp686N1150, DKFZp686F07174

Gene Ontology Provided by GOA

Component Evidence Code Pubs
integral component of membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
Preferred Names
transmembrane protein 184B
Names
putative MAPK-activating protein FM08

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001195071.1NP_001182000.1  transmembrane protein 184B isoform a

    See identical proteins and their annotated locations for NP_001182000.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) contains a different 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein (isoform a).
    Source sequence(s)
    AL020993, AL021977, BQ004586, BX648345
    Consensus CDS
    CCDS13969.2
    UniProtKB/Swiss-Prot
    Q9Y519
    UniProtKB/TrEMBL
    A0A024R1S0
    Related
    ENSP00000354441.4, OTTHUMP00000082609, ENST00000361684.8, OTTHUMT00000157101
    Conserved Domains (1) summary
    pfam03619
    Location:48317
    Solute_trans_a; Organic solute transporter Ostalpha
  2. NM_001195072.1NP_001182001.1  transmembrane protein 184B isoform b

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) contains an alternate segment, which results in the use of a downstream, in-frame, start codon, compared to variant 1. The predicted protein (isoform b) has a shorter N-terminus when it is compared to isoform a.
    Source sequence(s)
    AK292652, BC012983, BI197128, BQ004586, CR749859
    UniProtKB/Swiss-Prot
    Q9Y519
    Conserved Domains (1) summary
    pfam03619
    Location:1251
    Solute_trans_a; Organic solute transporter Ostalpha
  3. NM_012264.4NP_036396.2  transmembrane protein 184B isoform a

    See identical proteins and their annotated locations for NP_036396.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) is the most frequently occurring transcript variant. The resulting protein (isoform a) is the longer protein. Variants 1 and 2 encode the same protein.
    Source sequence(s)
    AK292652, BC012983, BQ004586
    Consensus CDS
    CCDS13969.2
    UniProtKB/Swiss-Prot
    Q9Y519
    UniProtKB/TrEMBL
    A0A024R1S0
    Related
    ENSP00000355210.3, OTTHUMP00000028772, ENST00000361906.7, OTTHUMT00000075445
    Conserved Domains (1) summary
    pfam03619
    Location:48317
    Solute_trans_a; Organic solute transporter Ostalpha

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000022.11 Reference GRCh38.p12 Primary Assembly

    Range
    38219291..38273034 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011530113.1XP_011528415.1  transmembrane protein 184B isoform X4

    See identical proteins and their annotated locations for XP_011528415.1

    Conserved Domains (1) summary
    pfam03619
    Location:46317
    Solute_trans_a; Organic solute transporter Ostalpha
  2. XM_017028756.1XP_016884245.1  transmembrane protein 184B isoform X5

    Related
    ENSP00000488878.1, OTTHUMP00000281122, ENST00000633438.1, OTTHUMT00000487952
    Conserved Domains (1) summary
    pfam03619
    Location:46317
    Solute_trans_a; Organic solute transporter Ostalpha
  3. XM_011530117.1XP_011528419.1  transmembrane protein 184B isoform X8

    See identical proteins and their annotated locations for XP_011528419.1

    Conserved Domains (1) summary
    pfam03619
    Location:1251
    Solute_trans_a; Organic solute transporter Ostalpha
  4. XM_017028759.1XP_016884248.1  transmembrane protein 184B isoform X10

  5. XM_011530119.1XP_011528421.1  transmembrane protein 184B isoform X9

    Conserved Domains (1) summary
    pfam03619
    Location:4201
    Solute_trans_a; Organic solute transporter Ostalpha
  6. XM_011530118.1XP_011528420.1  transmembrane protein 184B isoform X8

    See identical proteins and their annotated locations for XP_011528420.1

    Conserved Domains (1) summary
    pfam03619
    Location:1251
    Solute_trans_a; Organic solute transporter Ostalpha
  7. XM_024452210.1XP_024307978.1  transmembrane protein 184B isoform X11

    Conserved Domains (1) summary
    pfam03619
    Location:9177
    Solute_trans_a; Organic solute transporter Ostalpha
  8. XM_024452211.1XP_024307979.1  transmembrane protein 184B isoform X12

    Conserved Domains (1) summary
    pfam03619
    Location:9177
    Solute_trans_a; Organic solute transporter Ostalpha
  9. XM_017028754.2XP_016884243.1  transmembrane protein 184B isoform X1

  10. XM_011530112.2XP_011528414.2  transmembrane protein 184B isoform X2

  11. XM_017028755.1XP_016884244.1  transmembrane protein 184B isoform X3

  12. XM_011530114.1XP_011528416.1  transmembrane protein 184B isoform X4

    See identical proteins and their annotated locations for XP_011528416.1

    Conserved Domains (1) summary
    pfam03619
    Location:46317
    Solute_trans_a; Organic solute transporter Ostalpha
  13. XM_011530115.3XP_011528417.1  transmembrane protein 184B isoform X6

    Conserved Domains (1) summary
    pfam03619
    Location:96293
    Solute_trans_a; Organic solute transporter Ostalpha
  14. XM_017028757.1XP_016884246.1  transmembrane protein 184B isoform X7

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