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OR4C3 olfactory receptor family 4 subfamily C member 3 [ Homo sapiens (human) ]

Gene ID: 256144, updated on 27-Nov-2024

Summary

Official Symbol
OR4C3provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily C member 3provided by HGNC
Primary source
HGNC:HGNC:14697
See related
Ensembl:ENSG00000176547 AllianceGenome:HGNC:14697
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR11-98
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR4C3 in Genome Data Viewer
Location:
11p11.2
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 11 NC_000011.10 (48324920..48325955)
RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 11 NC_060935.1 (48494513..48495548)
RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (48346472..48347507)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene NANOG hESC enhancer GRCh37_chr11:48294091-48294729 Neighboring gene olfactory receptor family 4 subfamily X member 1 Neighboring gene olfactory receptor family 4 subfamily S member 1 Neighboring gene olfactory receptor family 4 subfamily C member 4 pseudogene Neighboring gene olfactory receptor family 4 subfamily C member 5

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
olfactory receptor 4C3
Names
olfactory receptor OR11-98

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004702.2NP_001004702.2  olfactory receptor 4C3

    Status: VALIDATED

    Source sequence(s)
    BC136853
    Consensus CDS
    CCDS31489.2
    UniProtKB/Swiss-Prot
    B2RNF2, Q6IFB3, Q8NH37
    UniProtKB/TrEMBL
    A0A126GVR6, A0A126GW65
    Related
    ENSP00000321419.5, ENST00000319856.5
    Conserved Domains (1) summary
    cd15939
    Location:23289
    7tmA_OR4A-like; olfactory receptor 4A and related proteins, member of the class A family of seven-transmembrane G protein-coupled receptors

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p14 Primary Assembly

    Range
    48324920..48325955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060935.1 Alternate T2T-CHM13v2.0

    Range
    48494513..48495548
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)