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TCP11L2 t-complex 11 like 2 [ Homo sapiens (human) ]

Gene ID: 255394, updated on 10-Oct-2019

Summary

Official Symbol
TCP11L2provided by HGNC
Official Full Name
t-complex 11 like 2provided by HGNC
Primary source
HGNC:HGNC:28627
See related
Ensembl:ENSG00000166046
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in esophagus (RPKM 5.7), lung (RPKM 5.0) and 25 other tissues See more
Orthologs

Genomic context

See TCP11L2 in Genome Data Viewer
Location:
12q23.3
Exon count:
16
Annotation release Status Assembly Chr Location
109.20190905 current GRCh38.p13 (GCF_000001405.39) 12 NC_000012.12 (106302026..106347455)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 12 NC_000012.11 (106696570..106741365)

Chromosome 12 - NC_000012.12Genomic Context describing neighboring genes Neighboring gene Sharpr-MPRA regulatory region 12855 Neighboring gene RNA, U7 small nuclear 94 pseudogene Neighboring gene RNA polymerase III subunit B Neighboring gene uncharacterized LOC100287944 Neighboring gene regulatory factor X4 Neighboring gene uncharacterized LOC100505978

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC40368

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
T-complex protein 11-like protein 2
Names
t-complex 11, testis-specific-like 2

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001286262.2NP_001273191.1  T-complex protein 11-like protein 2 isoform 2

    See identical proteins and their annotated locations for NP_001273191.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks multiple 3' exons and contains an alternate 3' terminal exon, resulting in a distinct 3' coding region and 3' UTR, compared to variant 1. The encoded isoform (2) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC079174, AC080012, BC017872, BC033617
    Consensus CDS
    CCDS66456.1
    UniProtKB/Swiss-Prot
    Q8N4U5
    Related
    ENSP00000448952.1, ENST00000547153.5
    Conserved Domains (1) summary
    pfam05794
    Location:77257
    Tcp11; T-complex protein 11
  2. NM_152772.3NP_689985.1  T-complex protein 11-like protein 2 isoform 1

    See identical proteins and their annotated locations for NP_689985.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AC079174, AC080012, BC033617
    Consensus CDS
    CCDS9104.1
    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Related
    ENSP00000299045.3, ENST00000299045.8
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20190905

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000012.12 Reference GRCh38.p13 Primary Assembly

    Range
    106302026..106347455
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017019131.1XP_016874620.1  T-complex protein 11-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  2. XM_011538132.3XP_011536434.1  T-complex protein 11-like protein 2 isoform X3

    Conserved Domains (1) summary
    pfam05794
    Location:77320
    Tcp11; T-complex protein 11
  3. XM_017019129.2XP_016874618.1  T-complex protein 11-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  4. XM_017019130.2XP_016874619.1  T-complex protein 11-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  5. XM_017019133.2XP_016874622.1  T-complex protein 11-like protein 2 isoform X2

    Conserved Domains (1) summary
    pfam05794
    Location:12432
    Tcp11; T-complex protein 11
  6. XM_017019132.2XP_016874621.1  T-complex protein 11-like protein 2 isoform X2

    Conserved Domains (1) summary
    pfam05794
    Location:12432
    Tcp11; T-complex protein 11
  7. XM_005268767.5XP_005268824.1  T-complex protein 11-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005268824.1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  8. XM_011538131.3XP_011536433.1  T-complex protein 11-like protein 2 isoform X2

    Conserved Domains (1) summary
    pfam05794
    Location:12432
    Tcp11; T-complex protein 11
  9. XM_011538130.2XP_011536432.1  T-complex protein 11-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011536432.1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  10. XM_005268768.4XP_005268825.1  T-complex protein 11-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005268825.1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  11. XM_011538129.3XP_011536431.1  T-complex protein 11-like protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011536431.1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
  12. XM_017019127.2XP_016874616.1  T-complex protein 11-like protein 2 isoform X1

    UniProtKB/Swiss-Prot
    Q8N4U5
    UniProtKB/TrEMBL
    A0A024RBH4
    Conserved Domains (1) summary
    pfam05794
    Location:77500
    Tcp11; T-complex protein 11
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