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VXN vexin [ Homo sapiens (human) ]

Gene ID: 254778, updated on 1-Aug-2020

Summary

Official Symbol
VXNprovided by HGNC
Official Full Name
vexinprovided by HGNC
Primary source
HGNC:HGNC:28498
See related
Ensembl:ENSG00000169085
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C8orf46
Expression
Biased expression in brain (RPKM 41.0) and prostate (RPKM 1.1) See more
Orthologs

Genomic context

See VXN in Genome Data Viewer
Location:
8q13.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 8 NC_000008.11 (66493566..66518524)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 8 NC_000008.10 (67405491..67430759)

Chromosome 8 - NC_000008.11Genomic Context describing neighboring genes Neighboring gene alcohol dehydrogenase iron containing 1 Neighboring gene TAF9 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 32kDa pseudogene Neighboring gene RNA, U6 small nuclear 1324, pseudogene Neighboring gene MYB proto-oncogene like 1 Neighboring gene uncharacterized LOC105375884

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Potential readthrough

Included gene: ADHFE1

Homology

Clone Names

  • MGC33510

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
neurogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron differentiation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
nucleus ISS
Inferred from Sequence or Structural Similarity
more info
 
plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
 

General protein information

Preferred Names
vexin
Names
uncharacterized protein C8orf46

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_152765.4NP_689978.2  vexin

    See identical proteins and their annotated locations for NP_689978.2

    Status: VALIDATED

    Source sequence(s)
    AK055047, BC028400, H17010
    Consensus CDS
    CCDS6191.2
    UniProtKB/Swiss-Prot
    Q8TAG6
    Related
    ENSP00000302260.3, ENST00000305454.8
    Conserved Domains (1) summary
    pfam15505
    Location:43207
    DUF4648; Domain of unknown function (DUF4648)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109.20200522

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000008.11 Reference GRCh38.p13 Primary Assembly

    Range
    66493566..66518524
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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