Format

Send to:

Choose Destination

ZDHHC24 zinc finger DHHC-type containing 24 [ Homo sapiens (human) ]

Gene ID: 254359, updated on 21-Apr-2019

Summary

Official Symbol
ZDHHC24provided by HGNC
Official Full Name
zinc finger DHHC-type containing 24provided by HGNC
Primary source
HGNC:HGNC:27387
See related
Ensembl:ENSG00000174165
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Ubiquitous expression in spleen (RPKM 1.8), kidney (RPKM 1.8) and 25 other tissues See more
Orthologs

Genomic context

See ZDHHC24 in Genome Data Viewer
Location:
11q13.2
Exon count:
9
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 11 NC_000011.10 (66520625..66546238, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (66288854..66313709, complement)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101928069 Neighboring gene pellino E3 ubiquitin protein ligase family member 3 Neighboring gene skeletal muscle cis-regulatory module in DPP3 intron Neighboring gene dipeptidyl peptidase 3 Neighboring gene Bardet-Biedl syndrome 1 Neighboring gene actinin alpha 3 (gene/pseudogene) Neighboring gene cathepsin F

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
probable palmitoyltransferase ZDHHC24
Names
DHHC-24
zinc finger DHHC domain-containing protein 24
zinc finger, DHHC domain containing 24
NP_001335500.1
NP_997223.1
XP_005273931.1
XP_011543195.1
XP_011543196.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001348571.1NP_001335500.1  probable palmitoyltransferase ZDHHC24 isoform 2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 3' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
    Source sequence(s)
    AK310561, DC406006
    Consensus CDS
    CCDS86218.1
    UniProtKB/TrEMBL
    E9PLR9
    Related
    ENSP00000431321.1, ENST00000526986.5
    Conserved Domains (1) summary
    cl19890
    Location:95169
    zf-DHHC; DHHC palmitoyltransferase
  2. NM_207340.3NP_997223.1  probable palmitoyltransferase ZDHHC24 isoform 1

    See identical proteins and their annotated locations for NP_997223.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    AP002748, AY358448
    Consensus CDS
    CCDS8143.1
    UniProtKB/Swiss-Prot
    Q6UX98
    Related
    ENSP00000309429.3, ENST00000310442.5
    Conserved Domains (1) summary
    pfam01529
    Location:95234
    zf-DHHC; DHHC palmitoyltransferase

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p12 Primary Assembly

    Range
    66520625..66546238 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005273874.4XP_005273931.1  probable palmitoyltransferase ZDHHC24 isoform X2

    See identical proteins and their annotated locations for XP_005273931.1

    UniProtKB/TrEMBL
    E9PI61
    Related
    ENSP00000436503.1, ENST00000534073.5
    Conserved Domains (1) summary
    cl19890
    Location:95169
    zf-DHHC; DHHC palmitoyltransferase
  2. XM_011544894.2XP_011543196.1  probable palmitoyltransferase ZDHHC24 isoform X2

    See identical proteins and their annotated locations for XP_011543196.1

    UniProtKB/TrEMBL
    E9PI61
    Conserved Domains (1) summary
    cl19890
    Location:95169
    zf-DHHC; DHHC palmitoyltransferase
  3. XM_011544893.3XP_011543195.1  probable palmitoyltransferase ZDHHC24 isoform X1

    Conserved Domains (1) summary
    cl19890
    Location:95169
    zf-DHHC; DHHC palmitoyltransferase

RNA

  1. XR_001747823.2 RNA Sequence

  2. XR_949860.3 RNA Sequence

Support Center