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dph3 diphthamide biosynthesis protein Dph3 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2543434, updated on 18-Sep-2024

Summary

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Official Symbol
dph3
Official Full Name
diphthamide biosynthesis protein Dph3
Primary source
PomBase:SPAC8F11.02c
Locus tag
SPOM_SPAC8F11.02C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
4
Sequence:
Chromosome: I; NC_003424.3 (2854405..2855694, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribosome biogenesis protein Ltv1 Neighboring gene 60S ribosomal protein eL41 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene DNA mismatch repair protein

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents. Villahermosa D, et al. Curr Genet, 2017 Dec. PMID 28555368, Free PMC Article
  2. Elp3 and Dph3 of Schizosaccharomyces pombe mediate cellular stress responses through tRNA(Lys)(UUU) modifications. Villahermosa D, et al. Sci Rep, 2017 Aug 3. PMID 28775286, Free PMC Article
  3. Large scale screening of genetic interaction with sgf73(+) in fission yeast. Guo Y, et al. Yi Chuan, 2014 Jul. PMID 25076038
  4. Yeast X-chromosome-associated protein 5 (Xap5) functions with H2A.Z to suppress aberrant transcripts. Anver S, et al. EMBO Rep, 2014 Aug. PMID 24957674, Free PMC Article
  5. A central role for TOR signalling in a yeast model for juvenile CLN3 disease. Bond ME, et al. Microb Cell, 2015 Nov 11. PMID 28357272, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents.
    Title: A mutated dph3 gene causes sensitivity of Schizosaccharomyces pombe cells to cytotoxic agents.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables ferrous iron binding ISS
Inferred from Sequence or Structural Similarity
more info
  
enables iron chaperone activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in protein histidyl modification to diphthamide ISO
Inferred from Sequence Orthology
more info
  
involved_in tRNA wobble base 5-methoxycarbonylmethyl-2-thiouridinylation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytosol HDA PubMed 
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
diphthamide biosynthesis protein Dph3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    2854405..2855694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356085.2 → NP_001342897.1  diphthamide biosynthesis protein Dph3 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UT33
    Conserved Domains (1) summary
    COG5216
    Location:1 → 67
    COG5216; Uncharacterized conserved protein [Function unknown]
Nucleotide Protein
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