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cut20 anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2542615, updated on 18-Sep-2024

Summary

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Official Symbol
cut20
Official Full Name
anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20
Primary source
PomBase:SPAC19G12.01c
Locus tag
SPOM_SPAC19G12.01C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
Also known as
apc4; lid1; SPAPJ698.04c
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Genomic context

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Location:
chromosome: I
Exon count:
5
Sequence:
Chromosome: I; NC_003424.3 (4041809..4044624, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene U2 snRNP-associated protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene MutL family mismatch-repair protein Pms1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Slow checkpoint activation kinetics as a safety device in anaphase. Kamenz J, et al. Curr Biol, 2014 Mar 17. PMID 24583014
  2. Fission yeast mfr1 activates APC and coordinates meiotic nuclear division with sporulation. Blanco MA, et al. J Cell Sci, 2001 Jun. PMID 11493649
  3. Study of cyclin proteolysis in anaphase-promoting complex (APC) mutant cells reveals the requirement for APC function in the final steps of the fission yeast septation initiation network. Chang L, et al. Mol Cell Biol, 2001 Oct. PMID 11533255, Free PMC Article
  4. The schizosaccharomyces pombe dim1(+) gene interacts with the anaphase-promoting complex or cyclosome (APC/C) component lid1(+) and is required for APC/C function. Berry LD, et al. Mol Cell Biol, 1999 Apr. PMID 10082519, Free PMC Article
  5. Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests. Zich J, et al. PLoS Genet, 2016 Feb. PMID 26882497, Free PMC Article

See all (26) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. Data suggest that Dim1p participates in pre-mRNA splicing, and in the nuclear export of lid1(+) mRNA.
    Title: Dim1p is required for efficient splicing and export of mRNA encoding lid1p, a component of the fission yeast anaphase-promoting complex.
Submit: New GeneRIF Correction

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in anaphase-promoting complex-dependent catabolic process EXP
Inferred from Experiment
more info
 PubMed 
involved_in anaphase-promoting complex-dependent catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in anaphase-promoting complex-dependent catabolic process IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in mitotic sister chromatid separation IMP
Inferred from Mutant Phenotype
more info
 PubMed 
involved_in protein K11-linked ubiquitination IBA
Inferred from Biological aspect of Ancestor
more info
  
Component Evidence Code Pubs
part_of anaphase-promoting complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of anaphase-promoting complex IDA
Inferred from Direct Assay
more info
 PubMed 
is_active_in cell division site HDA PubMed 
is_active_in cytosol HDA PubMed 
is_active_in mitotic spindle pole body HDA PubMed 
is_active_in nuclear periphery IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 

General protein information

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Preferred Names
anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    4041809..4044624 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001356148.2 → NP_001342965.1  anaphase-promoting complex platform subcomplex scaffold WD repeat subunit Apc4/Cut20 [Schizosaccharomyces pombe]

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    O42839, Q9P545
    Conserved Domains (3) summary
    sd00039
    Location:71 → 107
    7WD40; WD40 repeat [structural motif]
    pfam12894
    Location:33 → 122
    ANAPC4_WD40; Anaphase-promoting complex subunit 4 WD40 domain
    pfam12896
    Location:239 → 442
    ANAPC4; Anaphase-promoting complex, cyclosome, subunit 4
Nucleotide Protein
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