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lsm6 U6 snRNP-associated protein Lsm6 [ Schizosaccharomyces pombe (fission yeast) ]

Gene ID: 2541997, updated on 18-Sep-2024

Summary

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Official Symbol
lsm6
Official Full Name
U6 snRNP-associated protein Lsm6
Primary source
PomBase:SPAC2F3.17c
Locus tag
SPOM_SPAC2F3.17C
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Schizosaccharomyces pombe (strain: 972h-)
Lineage
Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina; Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae; Schizosaccharomyces
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Genomic context

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Location:
chromosome: I
Exon count:
3
Sequence:
Chromosome: I; NC_003424.3 (3923586..3924126, complement)

Chromosome I - NC_003424.3Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ribonuclease MRP complex subunit Neighboring gene inositol phosphorylceramide mannosyltransferase activity Imt1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene translocation subcomplex subunit Sec72

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_003424.3

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Structure of the LSm657 complex: an assembly intermediate of the LSm1-7 and LSm2-8 rings. Mund M, et al. J Mol Biol, 2011 Nov 25. PMID 22001694
  2. Crystal structures of Lsm3, Lsm4 and Lsm5/6/7 from Schizosaccharomyces pombe. Wu D, et al. PLoS One, 2012. PMID 22615807, Free PMC Article
  3. The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme. Porat J, et al. Nat Commun, 2022 Mar 11. PMID 35277511, Free PMC Article
  4. Molecular basis for the distinct cellular functions of the Lsm1-7 and Lsm2-8 complexes. Montemayor EJ, et al. RNA, 2020 Oct. PMID 32518066, Free PMC Article
  5. LARP7 family proteins have conserved function in telomerase assembly. Collopy LC, et al. Nat Commun, 2018 Feb 8. PMID 29422501, Free PMC Article

See all (10) citations in PubMed

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by PomBase

Function Evidence Code Pubs
enables RNA binding IBA
Inferred from Biological aspect of Ancestor
more info
  
enables U2 snRNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables poly(U) RNA binding IDA
Inferred from Direct Assay
more info
 PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
involved_in mRNA splicing, via spliceosome IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in maturation of SSU-rRNA IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in telomerase holoenzyme complex assembly TAS
Traceable Author Statement
more info
 PubMed 
Component Evidence Code Pubs
part_of Lsm1-7-Pat1 complex EXP
Inferred from Experiment
more info
 PubMed 
part_of Lsm2-8 complex EXP
Inferred from Experiment
more info
 PubMed 
is_active_in P-body IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U2 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U4/U6 x U5 tri-snRNP complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of U5 snRNP IDA
Inferred from Direct Assay
more info
 PubMed 
part_of U6 snRNP EXP
Inferred from Experiment
more info
 PubMed 
part_of U6 snRNP IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleolus IBA
Inferred from Biological aspect of Ancestor
more info
  
is_active_in nucleus HDA PubMed 
part_of sno(s)RNA-containing ribonucleoprotein complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of telomerase holoenzyme complex EXP
Inferred from Experiment
more info
 PubMed 

General protein information

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Preferred Names
U6 snRNP-associated protein Lsm6

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_003424.3 Reference assembly

    Range
    3923586..3924126 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001019801.3 → NP_594380.1  U6 snRNP-associated protein Lsm6 [Schizosaccharomyces pombe]

    See identical proteins and their annotated locations for NP_594380.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    Q9UUI1
    Conserved Domains (1) summary
    cd01726
    Location:4 → 71
    LSm6; Like-Sm protein 6
Nucleotide Protein
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