U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

GPATCH11 G-patch domain containing 11 [ Homo sapiens (human) ]

Gene ID: 253635, updated on 26-Oct-2022

Summary

Official Symbol
GPATCH11provided by HGNC
Official Full Name
G-patch domain containing 11provided by HGNC
Primary source
HGNC:HGNC:26768
See related
Ensembl:ENSG00000152133 AllianceGenome:HGNC:26768
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CENPY; CCDC75; CENP-Y
Summary
Predicted to enable nucleic acid binding activity. Located in kinetochore. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in fat (RPKM 17.4), testis (RPKM 7.9) and 23 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See GPATCH11 in Genome Data Viewer
Location:
2p22.2
Exon count:
11
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 2 NC_000002.12 (37084518..37099244)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 2 NC_060926.1 (37091653..37106376)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (37311661..37326387)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene striatin Neighboring gene RNA, U6 small nuclear 577, pseudogene Neighboring gene HEAT repeat containing 5B Neighboring gene eukaryotic translation initiation factor 2 alpha kinase 2 Neighboring gene ARL14EP pseudogene 1 Neighboring gene sulfotransferase family 6B member 1 Neighboring gene ribosomal protein L31 pseudogene 16

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ38348

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in kinetochore IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in kinetochore IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
G patch domain-containing protein 11
Names
centromere protein Y
coiled-coil domain containing 75
coiled-coil domain-containing protein 75
g patch domain-containing protein 11

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001278505.2NP_001265434.1  G patch domain-containing protein 11 isoform 2

    See identical proteins and their annotated locations for NP_001265434.1

    Status: VALIDATED

    Source sequence(s)
    AC007899
    UniProtKB/Swiss-Prot
    Q8N954
    Related
    ENSP00000281932.6, ENST00000281932.6
    Conserved Domains (1) summary
    pfam13821
    Location:108155
    DUF4187; Domain of unknown function (DUF4187)
  2. NM_001322249.4NP_001309178.3  G patch domain-containing protein 11 isoform 3

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Conserved Domains (3) summary
    COG5281
    Location:34166
    COG5281; Phage-related minor tail protein [Mobilome: prophages, transposons]
    pfam01585
    Location:74109
    G-patch; G-patch domain
    pfam13821
    Location:201248
    DUF4187; Domain of unknown function (DUF4187)
  3. NM_001371856.3NP_001358785.2  G patch domain-containing protein 11 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Conserved Domains (2) summary
    smart00443
    Location:74117
    G_patch; glycine rich nucleic binding domain
    pfam13821
    Location:223270
    DUF4187; Domain of unknown function (DUF4187)
  4. NM_001371858.3NP_001358787.2  G patch domain-containing protein 11 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Consensus CDS
    CCDS1785.4
    UniProtKB/TrEMBL
    A0A6I8PRS5
    Conserved Domains (2) summary
    pfam01585
    Location:74117
    G-patch; G-patch domain
    pfam13821
    Location:215262
    DUF4187; Domain of unknown function (DUF4187)
  5. NM_001371859.3NP_001358788.2  G patch domain-containing protein 11 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Consensus CDS
    CCDS1785.4
    UniProtKB/TrEMBL
    A0A6I8PRS5
    Conserved Domains (2) summary
    pfam01585
    Location:74117
    G-patch; G-patch domain
    pfam13821
    Location:215262
    DUF4187; Domain of unknown function (DUF4187)
  6. NM_001371860.3NP_001358789.2  G patch domain-containing protein 11 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Conserved Domains (2) summary
    smart00443
    Location:74116
    G_patch; glycine rich nucleic binding domain
    pfam13821
    Location:214261
    DUF4187; Domain of unknown function (DUF4187)
  7. NM_001371861.3NP_001358790.2  G patch domain-containing protein 11 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Conserved Domains (2) summary
    smart00443
    Location:74116
    G_patch; glycine rich nucleic binding domain
    pfam13821
    Location:214261
    DUF4187; Domain of unknown function (DUF4187)
  8. NM_001371862.3NP_001358791.2  G patch domain-containing protein 11 isoform 8

    Status: VALIDATED

    Source sequence(s)
    AC007899
    Conserved Domains (2) summary
    smart00443
    Location:74117
    G_patch; glycine rich nucleic binding domain
    pfam13821
    Location:212259
    DUF4187; Domain of unknown function (DUF4187)
  9. NM_174931.4NP_777591.4  G patch domain-containing protein 11 isoform 1

    Status: VALIDATED

    Source sequence(s)
    AC007899, AK095667, AK294697
    Consensus CDS
    CCDS1785.4
    UniProtKB/TrEMBL
    A0A6I8PRS5
    Related
    ENSP00000501347.1, ENST00000674370.2
    Conserved Domains (2) summary
    pfam01585
    Location:74117
    G-patch; G-patch domain
    pfam13821
    Location:215262
    DUF4187; Domain of unknown function (DUF4187)

RNA

  1. NR_163986.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007899
  2. NR_163987.1 RNA Sequence

    Status: VALIDATED

    Source sequence(s)
    AC007899

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p14 Primary Assembly

    Range
    37084518..37099244
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060926.1 Alternate T2T-CHM13v2.0

    Range
    37091653..37106376
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)