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EPHX4 epoxide hydrolase 4 [ Homo sapiens (human) ]

Gene ID: 253152, updated on 23-Nov-2021

Summary

Official Symbol
EPHX4provided by HGNC
Official Full Name
epoxide hydrolase 4provided by HGNC
Primary source
HGNC:HGNC:23758
See related
Ensembl:ENSG00000172031 MIM:617401
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
EH4; ABHD7; EPHXRP
Expression
Biased expression in brain (RPKM 5.0), thyroid (RPKM 1.1) and 9 other tissues See more
Orthologs
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Genomic context

See EPHX4 in Genome Data Viewer
Location:
1p22.1
Exon count:
7
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (92029985..92063538)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (92495542..92529095)

Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene transforming growth factor beta receptor 3 Neighboring gene RNA, 7SL, cytoplasmic 653, pseudogene Neighboring gene bromodomain testis associated Neighboring gene lysophosphatidylcholine acyltransferase 2b, pseudogene Neighboring gene SET like protein

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • FLJ90341

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables hydrolase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
epoxide hydrolase 4
Names
abhydrolase domain containing 7
abhydrolase domain-containing protein 7
epoxide hydrolase-related protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_173567.5NP_775838.3  epoxide hydrolase 4

    See identical proteins and their annotated locations for NP_775838.3

    Status: VALIDATED

    Source sequence(s)
    AC104836, AK074822, BC041475, DB475492
    Consensus CDS
    CCDS736.1
    UniProtKB/Swiss-Prot
    Q8IUS5
    Related
    ENSP00000359410.4, ENST00000370383.5
    Conserved Domains (1) summary
    COG0596
    Location:76350
    MhpC; Pimeloyl-ACP methyl ester carboxylesterase [Coenzyme transport and metabolism, General function prediction only]

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

    Range
    92029985..92063538
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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