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FUT5 fucosyltransferase 5 [ Homo sapiens (human) ]

Gene ID: 2527, updated on 22-Sep-2022

Summary

Official Symbol
FUT5provided by HGNC
Official Full Name
fucosyltransferase 5provided by HGNC
Primary source
HGNC:HGNC:4016
See related
Ensembl:ENSG00000130383 MIM:136835; AllianceGenome:HGNC:4016
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
FUC-TV
Summary
Enables 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity and 4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity. Involved in ceramide metabolic process and oligosaccharide metabolic process. Predicted to be located in Golgi membrane. [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon (RPKM 6.2), esophagus (RPKM 5.3) and 8 other tissues See more
Orthologs
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Genomic context

See FUT5 in Genome Data Viewer
Location:
19p13.3
Exon count:
2
Annotation release Status Assembly Chr Location
110 current GRCh38.p14 (GCF_000001405.40) 19 NC_000019.10 (5865826..5870540, complement)
110 current T2T-CHM13v2.0 (GCF_009914755.1) 19 NC_060943.1 (5853268..5857965, complement)
105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (5865837..5870551, complement)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene fucosyltransferase 6 Neighboring gene uncharacterized LOC101928844 Neighboring gene fucosyltransferase 3 (Lewis blood group) Neighboring gene Sharpr-MPRA regulatory region 10376 Neighboring gene NADH:ubiquinone oxidoreductase subunit A11 Neighboring gene Sharpr-MPRA regulatory region 9916

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in Golgi apparatus TAS
Traceable Author Statement
more info
PubMed 
located_in Golgi cisterna membrane IEA
Inferred from Electronic Annotation
more info
 
located_in Golgi membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5
Names
3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase FUT5
alpha (1,3) fucosyltransferase
alpha-(1,3)-fucosyltransferase 5
fucT-V
fucosyltransferase V
galactoside 3-L-fucosyltransferase
NP_002025.2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_002034.2NP_002025.2  4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT5

    Status: VALIDATED

    Source sequence(s)
    AC024592
    Consensus CDS
    CCDS12154.1
    UniProtKB/Swiss-Prot
    Q11128
    UniProtKB/TrEMBL
    K7ENC0
    Related
    ENSP00000466880.1, ENST00000588525.1
    Conserved Domains (2) summary
    pfam00852
    Location:202370
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:73183
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p14 Primary Assembly

    Range
    5865826..5870540 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Reference GRCh38.p14 PATCHES

Genomic

  1. NW_025791810.1 Reference GRCh38.p14 PATCHES

    Range
    39407..44105 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate T2T-CHM13v2.0

Genomic

  1. NC_060943.1 Alternate T2T-CHM13v2.0

    Range
    5853268..5857965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)