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Psmd13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 [ Mus musculus (house mouse) ]

Gene ID: 23997, updated on 30-Apr-2024

Summary

Official Symbol
Psmd13provided by MGI
Official Full Name
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13provided by MGI
Primary source
MGI:MGI:1345192
See related
Ensembl:ENSMUSG00000025487 AllianceGenome:MGI:1345192
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
S11
Summary
Predicted to enable endopeptidase activity and structural molecule activity. Acts upstream of or within meiosis I. Part of proteasome regulatory particle. Is expressed in diencephalon lateral wall ventricular layer; medulla oblongata alar plate ventricular layer; rest of cerebellum ventricular layer; telencephalon ventricular layer; and trunk mesenchyme. Orthologous to human PSMD13 (proteasome 26S subunit, non-ATPase 13). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in CNS E11.5 (RPKM 64.9), placenta adult (RPKM 48.5) and 28 other tissues See more
Orthologs
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Genomic context

See Psmd13 in Genome Data Viewer
Location:
7 F5; 7 86.09 cM
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (140462307..140478555)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (140882394..140898642)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E1748 Neighboring gene Bet1 golgi vesicular membrane trafficking protein like Neighboring gene RIC8 guanine nucleotide exchange factor A Neighboring gene sirtuin 3 Neighboring gene STARR-positive B cell enhancer ABC_E9304 Neighboring gene DnaJ (Hsp40) homolog, subfamily A, member 1 pseudogene Neighboring gene cytochrome c oxidase subunit 8B Neighboring gene cDNA sequence BC023486

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables endopeptidase activity ISA
Inferred from Sequence Alignment
more info
PubMed 
enables structural molecule activity IBA
Inferred from Biological aspect of Ancestor
more info
 
Process Evidence Code Pubs
acts_upstream_of_or_within meiosis I IMP
Inferred from Mutant Phenotype
more info
PubMed 
involved_in ubiquitin-dependent protein catabolic process IBA
Inferred from Biological aspect of Ancestor
more info
 
Component Evidence Code Pubs
is_active_in cytosol IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of proteasome accessory complex IDA
Inferred from Direct Assay
more info
PubMed 
part_of proteasome complex ISO
Inferred from Sequence Orthology
more info
 
part_of proteasome regulatory particle IDA
Inferred from Direct Assay
more info
PubMed 
part_of proteasome regulatory particle, lid subcomplex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
26S proteasome non-ATPase regulatory subunit 13
Names
26S proteasome regulatory subunit RPN9
26S proteasome regulatory subunit S11
26S proteasome regulatory subunit p40.5
26S proteasome subunit p40.5

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_011875.4NP_036005.1  26S proteasome non-ATPase regulatory subunit 13

    See identical proteins and their annotated locations for NP_036005.1

    Status: PROVISIONAL

    Source sequence(s)
    AC107815
    Consensus CDS
    CCDS21990.1
    UniProtKB/Swiss-Prot
    Q3TB19, Q3TR74, Q542R0, Q9WVJ2
    UniProtKB/TrEMBL
    B2RT97, E9Q5I9
    Related
    ENSMUSP00000026560.8, ENSMUST00000026560.14
    Conserved Domains (1) summary
    pfam01399
    Location:231335
    PCI; PCI domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    140462307..140478555
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)