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Rtp3 receptor transporter protein 3 [ Mus musculus (house mouse) ]

Gene ID: 235636, updated on 17-Aug-2024

Summary

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Official Symbol
Rtp3provided by MGI
Official Full Name
receptor transporter protein 3provided by MGI
Primary source
MGI:MGI:2446841
See related
Ensembl:ENSMUSG00000066319 AllianceGenome:MGI:2446841
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Tmem7
Summary
Predicted to enable olfactory receptor binding activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of bitter taste; protein insertion into membrane; and protein targeting to membrane. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in cytoplasm. Orthologous to human RTP3 (receptor transporter protein 3). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in liver E18 (RPKM 10.9), liver E14.5 (RPKM 9.7) and 10 other tissues See more
Orthologs
human all
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Genomic context

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Location:
9 F2; 9 60.79 cM
Exon count:
2
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (110814003..110818781, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (110984935..110990265, complement)

Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene CRISPRi-validated Tdgf1 proximal enhancer Neighboring gene cripto, EGF-CFC family member Neighboring gene leucine rich repeat containing 2 Neighboring gene predicted gene 10030 Neighboring gene lactotransferrin Neighboring gene C-C motif chemokine receptor-like 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Comparative human/murine sequence analysis of the common eliminated region 1 from human 3p21.3. Kiss H, et al. Mamm Genome, 2002 Nov. PMID 12461651
  2. RTP family members induce functional expression of mammalian odorant receptors. Saito H, et al. Cell, 2004 Nov 24. PMID 15550249
  3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
  4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

General gene information

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Homology

Clone Names

  • MGC118000

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
enables olfactory receptor binding IBA
Inferred from Biological aspect of Ancestor
more info
  
Process Evidence Code Pubs
involved_in detection of chemical stimulus involved in sensory perception of bitter taste IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in detection of chemical stimulus involved in sensory perception of bitter taste ISO
Inferred from Sequence Orthology
more info
  
involved_in protein insertion into membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to membrane IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in protein targeting to membrane ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in cytoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
receptor-transporting protein 3
Names
transmembrane protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153100.2 → NP_694740.2  receptor-transporting protein 3

    See identical proteins and their annotated locations for NP_694740.2

    Status: VALIDATED

    Source sequence(s)
    AC118727
    Consensus CDS
    CCDS81087.1
    UniProtKB/Swiss-Prot
    E9QP29, Q2KHT1, Q5QGU6, Q8VDC2
    UniProtKB/TrEMBL
    B2RWS3
    Related
    ENSMUSP00000143305.2, ENSMUST00000199891.2
    Conserved Domains (2) summary
    pfam05109
    Location:214 → 393
    Herpes_BLLF1; Herpes virus major outer envelope glycoprotein (BLLF1)
    pfam13695
    Location:52 → 164
    zf-3CxxC; Zinc-binding domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000075.7 Reference GRCm39 C57BL/6J

    Range
    110814003..110818781 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036154920.1 → XP_036010813.1  receptor-transporting protein 3 isoform X1

    UniProtKB/TrEMBL
    B2RWS3
    Conserved Domains (2) summary
    PHA03247
    Location:171 → 453
    PHA03247; large tegument protein UL36; Provisional
    pfam13695
    Location:52 → 164
    zf-3CxxC; Zinc-binding domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5QGU6.2 GenPept UniProtKB/Swiss-Prot:Q5QGU6

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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