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SYNGR4 synaptogyrin 4 [ Homo sapiens (human) ]

Gene ID: 23546, updated on 23-Nov-2021

Summary

Official Symbol
SYNGR4provided by HGNC
Official Full Name
synaptogyrin 4provided by HGNC
Primary source
HGNC:HGNC:11502
See related
Ensembl:ENSG00000105467 MIM:608373
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
This gene encodes an integral membrane protein. The gene belongs to the synaptogyrin gene family. Like other members of the family the protein contains four transmembrane regions. The exact function of this protein is unclear. [provided by RefSeq, Jul 2008]
Expression
Restricted expression toward testis (RPKM 8.9) See more
Orthologs
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Genomic context

See SYNGR4 in Genome Data Viewer
Location:
19q13.33
Exon count:
8
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 19 NC_000019.10 (48364267..48376377)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 19 NC_000019.9 (48867624..48879634)

Chromosome 19 - NC_000019.10Genomic Context describing neighboring genes Neighboring gene epithelial membrane protein 3 Neighboring gene transmembrane protein 143 Neighboring gene uncharacterized LOC107984140 Neighboring gene KDEL endoplasmic reticulum protein retention receptor 1 Neighboring gene glutamate ionotropic receptor NMDA type subunit 2D

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC125805

Gene Ontology Provided by GOA

Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in neuromuscular junction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
is_active_in synaptic vesicle membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
synaptogyrin-4
Names
testis tissue sperm-binding protein Li 72n

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_012451.4NP_036583.2  synaptogyrin-4

    See identical proteins and their annotated locations for NP_036583.2

    Status: REVIEWED

    Source sequence(s)
    AC011514, AI222412, BC106891
    Consensus CDS
    CCDS12717.1
    UniProtKB/Swiss-Prot
    O95473
    UniProtKB/TrEMBL
    A0A140VKF5
    Related
    ENSP00000344041.1, ENST00000344846.7
    Conserved Domains (1) summary
    pfam01284
    Location:18163
    MARVEL; Membrane-associating domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000019.10 Reference GRCh38.p13 Primary Assembly

    Range
    48364267..48376377
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005258693.3XP_005258750.1  synaptogyrin-4 isoform X1

    See identical proteins and their annotated locations for XP_005258750.1

    UniProtKB/Swiss-Prot
    O95473
    UniProtKB/TrEMBL
    A0A140VKF5
    Conserved Domains (1) summary
    pfam01284
    Location:18163
    MARVEL; Membrane-associating domain
  2. XM_005258694.2XP_005258751.1  synaptogyrin-4 isoform X1

    See identical proteins and their annotated locations for XP_005258751.1

    UniProtKB/Swiss-Prot
    O95473
    UniProtKB/TrEMBL
    A0A140VKF5
    Conserved Domains (1) summary
    pfam01284
    Location:18163
    MARVEL; Membrane-associating domain
  3. XM_011526686.2XP_011524988.1  synaptogyrin-4 isoform X2

    Conserved Domains (1) summary
    pfam01284
    Location:10114
    MARVEL; Membrane-associating domain
  4. XM_017026541.1XP_016882030.1  synaptogyrin-4 isoform X2

    Conserved Domains (1) summary
    pfam01284
    Location:10114
    MARVEL; Membrane-associating domain
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