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TMEM131 transmembrane protein 131 [ Homo sapiens (human) ]

Gene ID: 23505, updated on 7-Jun-2020

Summary

Official Symbol
TMEM131provided by HGNC
Official Full Name
transmembrane protein 131provided by HGNC
Primary source
HGNC:HGNC:30366
See related
Ensembl:ENSG00000075568 MIM:615659
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
RW1; CC28; YR-23; PRO1048
Expression
Ubiquitous expression in colon (RPKM 14.6), lymph node (RPKM 13.4) and 25 other tissues See more
Orthologs

Genomic context

See TMEM131 in Genome Data Viewer
Location:
2q11.2
Exon count:
42
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 2 NC_000002.12 (97756336..97996182, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (98372799..98612389, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene chromosome 2 open reading frame 92 Neighboring gene RNA, U4 small nuclear 8, pseudogene Neighboring gene zeta chain of T cell receptor associated protein kinase 70 Neighboring gene uncharacterized LOC107985921 Neighboring gene high mobility group nucleosome binding domain 1 pseudogene 36 Neighboring gene RNA, U7 small nuclear 96 pseudogene Neighboring gene MIR2 retrotransposon enhancer-blocking element Neighboring gene uncharacterized LOC105373501

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • KIAA0257

Gene Ontology Provided by GOA

Function Evidence Code Pubs
molecular_function ND
No biological Data available
more info
 
Process Evidence Code Pubs
biological_process ND
No biological Data available
more info
 
Component Evidence Code Pubs
cellular_component ND
No biological Data available
more info
 
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
transmembrane protein 131
Names
2610524E03Rik

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_015348.2NP_056163.1  transmembrane protein 131

    See identical proteins and their annotated locations for NP_056163.1

    Status: VALIDATED

    Source sequence(s)
    AC092591, AK025852, AK098792, AU132630, BE327511, D87446
    Consensus CDS
    CCDS46368.1
    UniProtKB/Swiss-Prot
    Q92545
    Related
    ENSP00000186436.5, ENST00000186436.10
    Conserved Domains (1) summary
    pfam12371
    Location:109191
    TMEM131_like; Transmembrane protein 131-like

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p13 Primary Assembly

    Range
    97756336..97996182 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005263912.3XP_005263969.1  transmembrane protein 131 isoform X4

    Conserved Domains (1) summary
    cl13764
    Location:109162
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  2. XM_005263911.1XP_005263968.1  transmembrane protein 131 isoform X3

    Conserved Domains (1) summary
    cl13764
    Location:126179
    ASH; Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin
  3. XM_011510869.1XP_011509171.1  transmembrane protein 131 isoform X5

    Conserved Domains (1) summary
    pfam12371
    Location:126208
    TMEM131_like; Transmembrane protein 131-like
  4. XM_005263910.1XP_005263967.1  transmembrane protein 131 isoform X2

    Conserved Domains (1) summary
    pfam12371
    Location:126208
    TMEM131_like; Transmembrane protein 131-like
  5. XM_005263909.1XP_005263966.1  transmembrane protein 131 isoform X1

    Conserved Domains (1) summary
    pfam12371
    Location:126208
    TMEM131_like; Transmembrane protein 131-like

RNA

  1. XR_001738682.1 RNA Sequence

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