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Mpv17l2 MPV17 mitochondrial membrane protein-like 2 [ Mus musculus (house mouse) ]

Gene ID: 234384, updated on 2-Nov-2024

Summary

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Official Symbol
Mpv17l2provided by MGI
Official Full Name
MPV17 mitochondrial membrane protein-like 2provided by MGI
Primary source
MGI:MGI:2681846
See related
Ensembl:ENSMUSG00000035559 AllianceGenome:MGI:2681846
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Fksg24
Summary
Predicted to be involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in bone; genitourinary system; and gut. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Broad expression in adrenal adult (RPKM 118.7), stomach adult (RPKM 57.9) and 26 other tissues See more
Orthologs
human all
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Genomic context

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See Mpv17l2 in Genome Data Viewer
Location:
8 B3.3; 8 34.15 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (71211295..71213589, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70758649..70760932, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34255 Neighboring gene phosphodiesterase 4C, cAMP specific Neighboring gene STARR-positive B cell enhancer ABC_E1370 Neighboring gene RIKEN cDNA 6330537M06 gene Neighboring gene STARR-positive B cell enhancer ABC_E190 Neighboring gene RAB3A, member RAS oncogene family Neighboring gene STARR-positive B cell enhancer ABC_E10506 Neighboring gene interferon gamma inducible protein 30 Neighboring gene phosphoinositide-3-kinase regulatory subunit 2 Neighboring gene STARR-positive B cell enhancer ABC_E8241

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  4. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article
  5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

See all (14) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3) 

General gene information

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Markers

Homology

Clone Names

  • MGC63135

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in mitochondrial ribosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in mitochondrial ribosome assembly IEA
Inferred from Electronic Annotation
more info
  
involved_in mitochondrial ribosome assembly ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mitochondrial translation ISO
Inferred from Sequence Orthology
more info
  
involved_in positive regulation of mitochondrial translation ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
  
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
  
located_in mitochondrial inner membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
  
part_of mitochondrial large ribosomal subunit ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
mpv17-like protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183170.2 → NP_898993.1  mpv17-like protein 2

    See identical proteins and their annotated locations for NP_898993.1

    Status: PROVISIONAL

    Source sequence(s)
    CAAA01070179
    Consensus CDS
    CCDS22380.1
    UniProtKB/Swiss-Prot
    Q3THH2, Q80UR1, Q8VIK2
    Related
    ENSMUSP00000037929.9, ENSMUST00000038626.10
    Conserved Domains (1) summary
    pfam04117
    Location:124 → 186
    Mpv17_PMP22; Mpv17 / PMP22 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000074.7 Reference GRCm39 C57BL/6J

    Range
    71211295..71213589 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242299.3 → XP_011240601.1  mpv17-like protein 2 isoform X1

    Conserved Domains (1) summary
    pfam04117
    Location:28 → 89
    Mpv17_PMP22; Mpv17 / PMP22 family
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8VIK2.1 GenPept UniProtKB/Swiss-Prot:Q8VIK2

Gene LinkOut

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