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Mpv17l2 MPV17 mitochondrial membrane protein-like 2 [ Mus musculus (house mouse) ]

Gene ID: 234384, updated on 12-May-2024


Official Symbol
Mpv17l2provided by MGI
Official Full Name
MPV17 mitochondrial membrane protein-like 2provided by MGI
Primary source
See related
Ensembl:ENSMUSG00000035559 AllianceGenome:MGI:2681846
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Predicted to be involved in mitochondrial ribosome assembly and positive regulation of mitochondrial translation. Located in mitochondrion. Is expressed in bone; genitourinary system; and gut. Orthologous to human MPV17L2 (MPV17 mitochondrial inner membrane protein like 2). [provided by Alliance of Genome Resources, Apr 2022]
Broad expression in adrenal adult (RPKM 118.7), stomach adult (RPKM 57.9) and 26 other tissues See more
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Genomic context

See Mpv17l2 in Genome Data Viewer
8 B3.3; 8 34.15 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (71211295..71213589, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (70758649..70760932, complement)

Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34255 Neighboring gene phosphodiesterase 4C, cAMP specific Neighboring gene STARR-positive B cell enhancer ABC_E1370 Neighboring gene RIKEN cDNA 6330537M06 gene Neighboring gene STARR-positive B cell enhancer ABC_E190 Neighboring gene RAB3A, member RAS oncogene family Neighboring gene STARR-positive B cell enhancer ABC_E10506 Neighboring gene interferon gamma inducible protein 30 Neighboring gene phosphoinositide-3-kinase regulatory subunit 2 Neighboring gene STARR-positive B cell enhancer ABC_E8241

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3) 

General gene information


Clone Names

  • MGC63135

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
Process Evidence Code Pubs
involved_in mitochondrial ribosome assembly IBA
Inferred from Biological aspect of Ancestor
more info
involved_in mitochondrial ribosome assembly ISO
Inferred from Sequence Orthology
more info
involved_in positive regulation of mitochondrial translation ISO
Inferred from Sequence Orthology
more info
Component Evidence Code Pubs
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
located_in membrane IEA
Inferred from Electronic Annotation
more info
located_in mitochondrial inner membrane ISO
Inferred from Sequence Orthology
more info
part_of mitochondrial large ribosomal subunit ISO
Inferred from Sequence Orthology
more info
located_in mitochondrion HDA PubMed 
is_active_in mitochondrion IBA
Inferred from Biological aspect of Ancestor
more info

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183170.2NP_898993.1  mpv17-like protein 2

    See identical proteins and their annotated locations for NP_898993.1


    Source sequence(s)
    Consensus CDS
    Q3THH2, Q80UR1, Q8VIK2
    ENSMUSP00000037929.9, ENSMUST00000038626.10
    Conserved Domains (1) summary
    Mpv17_PMP22; Mpv17 / PMP22 family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000074.7 Reference GRCm39 C57BL/6J

    71211295..71213589 complement
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011242299.3XP_011240601.1  mpv17-like protein 2 isoform X1

    Conserved Domains (1) summary
    Mpv17_PMP22; Mpv17 / PMP22 family