U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Cog7 component of oligomeric golgi complex 7 [ Mus musculus (house mouse) ]

Gene ID: 233824, updated on 18-Sep-2024

Summary

Go to the top of the page Help
Official Symbol
Cog7provided by MGI
Official Full Name
component of oligomeric golgi complex 7provided by MGI
Primary source
MGI:MGI:2685013
See related
Ensembl:ENSMUSG00000034951 AllianceGenome:MGI:2685013
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Gm167; 5630400E24Rik
Summary
Predicted to be involved in several processes, including protein localization to Golgi apparatus; protein stabilization; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within protein transport. Predicted to be located in Golgi apparatus and nucleolus. Predicted to be part of Golgi transport complex. Is expressed in lung; metanephros; pancreas; submandibular gland; and testis. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIe. Orthologous to human COG7 (component of oligomeric golgi complex 7). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in testis adult (RPKM 17.2), kidney adult (RPKM 15.7) and 28 other tissues See more
Orthologs
human all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
7 F2; 7 65.09 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (121522059..121580940, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (121922836..121981719, complement)

Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene sodium channel, nonvoltage-gated 1 gamma Neighboring gene STARR-seq mESC enhancer starr_20067 Neighboring gene predicted gene, 36848 Neighboring gene STARR-seq mESC enhancer starr_20068 Neighboring gene sodium channel, nonvoltage-gated 1 beta Neighboring gene STARR-seq mESC enhancer starr_20069 Neighboring gene STARR-positive B cell enhancer ABC_E10471 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 2 Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial Neighboring gene ubiquitin family domain containing 1

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help
  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. A mouse knockout library for secreted and transmembrane proteins. Tang T, et al. Nat Biotechnol, 2010 Jul. PMID 20562862
  2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
  3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
  4. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
  5. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article

See all (13) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Targeted (3)  1 citation

Pathways from PubChem

Go to the top of the page

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
  
Process Evidence Code Pubs
involved_in Golgi organization IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in Golgi organization ISO
Inferred from Sequence Orthology
more info
  
involved_in glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in intracellular protein transport IEA
Inferred from Electronic Annotation
more info
  
involved_in intracellular protein transport ISO
Inferred from Sequence Orthology
more info
  
involved_in protein glycosylation ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
involved_in protein localization to organelle ISO
Inferred from Sequence Orthology
more info
  
involved_in protein stabilization ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde transport, vesicle recycling within Golgi ISO
Inferred from Sequence Orthology
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus ISO
Inferred from Sequence Orthology
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
part_of Golgi transport complex IBA
Inferred from Biological aspect of Ancestor
more info
  
part_of Golgi transport complex IEA
Inferred from Electronic Annotation
more info
  
part_of Golgi transport complex ISO
Inferred from Sequence Orthology
more info
  
located_in intracellular membrane-bounded organelle ISO
Inferred from Sequence Orthology
more info
  
located_in nucleolus ISO
Inferred from Sequence Orthology
more info
  

General protein information

Go to the top of the page Help
Preferred Names
conserved oligomeric Golgi complex subunit 7
Names
COG complex subunit 7
NP_001028490.2
XP_006507762.2
XP_006507763.2
XP_030098374.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001033318.3 → NP_001028490.2  conserved oligomeric Golgi complex subunit 7

    See identical proteins and their annotated locations for NP_001028490.2

    Status: VALIDATED

    Source sequence(s)
    AK154693
    Consensus CDS
    CCDS21805.1
    UniProtKB/Swiss-Prot
    Q3U3L7, Q3UM29
    UniProtKB/TrEMBL
    A0A0R4J0Q9
    Related
    ENSMUSP00000058990.8, ENSMUST00000057576.8
    Conserved Domains (1) summary
    pfam10191
    Location:2 → 767
    COG7; Golgi complex component 7 (COG7)

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000073.7 Reference GRCm39 C57BL/6J

    Range
    121522059..121580940 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030242514.2 → XP_030098374.1  conserved oligomeric Golgi complex subunit 7 isoform X3

    UniProtKB/Swiss-Prot
    Q3U3L7, Q3UM29
    Conserved Domains (1) summary
    pfam10191
    Location:2 → 745
    COG7; Golgi complex component 7 (COG7)

  2. XM_006507700.4 → XP_006507763.2  conserved oligomeric Golgi complex subunit 7 isoform X2

    UniProtKB/Swiss-Prot
    Q3U3L7, Q3UM29
    Conserved Domains (1) summary
    pfam10191
    Location:2 → 757
    COG7; Golgi complex component 7 (COG7)

  3. XM_006507699.4 → XP_006507762.2  conserved oligomeric Golgi complex subunit 7 isoform X1

    UniProtKB/Swiss-Prot
    Q3U3L7, Q3UM29
    Conserved Domains (1) summary
    pfam10191
    Location:2 → 779
    COG7; Golgi complex component 7 (COG7)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q3UM29.1 GenPept UniProtKB/Swiss-Prot:Q3UM29

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information
Molecular Biology Databases
Research Materials
Tools
Miscellaneous