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Acad9 acyl-Coenzyme A dehydrogenase family, member 9 [ Mus musculus (house mouse) ]

Gene ID: 229211, updated on 10-Feb-2024

Summary

Official Symbol
Acad9provided by MGI
Official Full Name
acyl-Coenzyme A dehydrogenase family, member 9provided by MGI
Primary source
MGI:MGI:1914272
See related
Ensembl:ENSMUSG00000027710 AllianceGenome:MGI:1914272
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NPD002; 4732402K02; 2600017P15Rik; C630012L17Rik
Summary
Predicted to enable fatty-acyl-CoA binding activity; medium-chain-acyl-CoA dehydrogenase activity; and very-long-chain-acyl-CoA dehydrogenase activity. Predicted to be involved in long-chain fatty acid metabolic process; medium-chain fatty acid metabolic process; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency 20. Orthologous to human ACAD9 (acyl-CoA dehydrogenase family member 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in kidney adult (RPKM 7.6), CNS E11.5 (RPKM 7.2) and 28 other tissues See more
Orthologs
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Genomic context

See Acad9 in Genome Data Viewer
Location:
3 B; 3 17.41 cM
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (36120128..36147006)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (36065979..36092857)

Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene methylcrotonoyl-Coenzyme A carboxylase 1 (alpha) Neighboring gene STARR-positive B cell enhancer ABC_E650 Neighboring gene methylcrotonoyl-Coenzyme A carboxylase 1 (alpha), opposite strand Neighboring gene gene model 57858 Neighboring gene STARR-positive B cell enhancer ABC_E3429 Neighboring gene STARR-seq mESC enhancer starr_07416 Neighboring gene STARR-seq mESC enhancer starr_07417 Neighboring gene predicted gene, 54173 Neighboring gene STARR-positive B cell enhancer ABC_E10177 Neighboring gene zinc finger protein 267

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2)  1 citation
  • Endonuclease-mediated (4) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables acyl-CoA dehydrogenase activity IBA
Inferred from Biological aspect of Ancestor
more info
 
enables acyl-CoA dehydrogenase activity IEA
Inferred from Electronic Annotation
more info
 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 
enables long-chain fatty acyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables medium-chain fatty acyl-CoA dehydrogenase activity ISO
Inferred from Sequence Orthology
more info
 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 
enables oxidoreductase activity, acting on the CH-CH group of donors IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
involved_in long-chain fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in medium-chain fatty acid metabolic process ISO
Inferred from Sequence Orthology
more info
 
involved_in mitochondrial respiratory chain complex I assembly ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in dendrite ISO
Inferred from Sequence Orthology
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
 
located_in mitochondrial membrane ISO
Inferred from Sequence Orthology
more info
 
located_in mitochondrion HDA PubMed 
located_in mitochondrion ISO
Inferred from Sequence Orthology
more info
 
located_in nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
complex I assembly factor ACAD9, mitochondrial
Names
acyl-CoA dehydrogenase family member 9, mitochondrial
very-long-chain acyl-CoA dehydrogenase VLCAD homolog
NP_766266.3
XP_036018919.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172678.4NP_766266.3  complex I assembly factor ACAD9, mitochondrial

    See identical proteins and their annotated locations for NP_766266.3

    Status: VALIDATED

    Source sequence(s)
    AC158934, AK031820, AK145423
    Consensus CDS
    CCDS17310.1
    UniProtKB/Swiss-Prot
    Q3ULL9, Q8BK76, Q8C0B5, Q8JZN5
    Related
    ENSMUSP00000011492.9, ENSMUST00000011492.15
    Conserved Domains (1) summary
    cd01161
    Location:42449
    VLCAD; Very long chain acyl-CoA dehydrogenase

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000069.7 Reference GRCm39 C57BL/6J

    Range
    36120128..36147006
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036163026.1XP_036018919.1  complex I assembly factor ACAD9, mitochondrial isoform X1

    Conserved Domains (1) summary
    cl09933
    Location:1204
    ACAD; Acyl-CoA dehydrogenase

RNA

  1. XR_003954304.1 RNA Sequence