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Slc17a9 solute carrier family 17, member 9 [ Mus musculus (house mouse) ]

Gene ID: 228993, updated on 18-Apr-2024

Summary

Official Symbol
Slc17a9provided by MGI
Official Full Name
solute carrier family 17, member 9provided by MGI
Primary source
MGI:MGI:1919107
See related
Ensembl:ENSMUSG00000023393 AllianceGenome:MGI:1919107
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Vnut; 1700019H03Rik
Summary
Predicted to enable ADP transmembrane transporter activity; ATP transmembrane transporter activity; and guanine nucleotide transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to act upstream of or within ADP transport; ATP export; and guanine nucleotide transmembrane transport. Located in chromaffin granule membrane. Is expressed in esophagus; male reproductive gland or organ; and nasal cavity epithelium. Human ortholog(s) of this gene implicated in porokeratosis. Orthologous to human SLC17A9 (solute carrier family 17 member 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 55.9), genital fat pad adult (RPKM 48.4) and 13 other tissues See more
Orthologs
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Genomic context

Location:
2 H4; 2 103.28 cM
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (180363989..180384073)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (180724576..180742280)

Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene death inducer-obliterator 1 Neighboring gene STARR-positive B cell enhancer mm9_chr2:180436639-180436940 Neighboring gene STARR-seq mESC enhancer starr_06736 Neighboring gene predicted gene, 22502 Neighboring gene STARR-positive B cell enhancer ABC_E9213 Neighboring gene GID complex subunit 8 Neighboring gene predicted gene, 30455 Neighboring gene STARR-seq mESC enhancer starr_06739 Neighboring gene STARR-positive B cell enhancer ABC_E1614 Neighboring gene basic helix-loop-helix family, member e23 Neighboring gene predicted gene 14340

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (5)  1 citation
  • Gene trapped (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC28538

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in chromaffin granule membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in chromaffin granule membrane ISO
Inferred from Sequence Orthology
more info
PubMed 
located_in cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
is_active_in lysosomal membrane IDA
Inferred from Direct Assay
more info
PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in mucin granule ISO
Inferred from Sequence Orthology
more info
 
located_in secretory granule IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
voltage-gated purine nucleotide uniporter SLC17A9
Names
vesicular nucleotide transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_183161.3NP_898984.3  voltage-gated purine nucleotide uniporter SLC17A9

    See identical proteins and their annotated locations for NP_898984.3

    Status: VALIDATED

    Source sequence(s)
    AK006122, AW554829, BE850231, BG087579, CF165170
    Consensus CDS
    CCDS38378.1
    UniProtKB/Swiss-Prot
    A2AJ51, Q8VCL5
    Related
    ENSMUSP00000091771.4, ENSMUST00000094218.4
    Conserved Domains (2) summary
    cd06174
    Location:40432
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00893
    Location:43424
    2A0114; D-galactonate transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000068.8 Reference GRCm39 C57BL/6J

    Range
    180363989..180384073
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006500591.3XP_006500654.1  voltage-gated purine nucleotide uniporter SLC17A9 isoform X2

    Conserved Domains (1) summary
    cl28910
    Location:112367
    MFS; Major Facilitator Superfamily
  2. XM_006500589.3XP_006500652.1  voltage-gated purine nucleotide uniporter SLC17A9 isoform X1

    See identical proteins and their annotated locations for XP_006500652.1

    Conserved Domains (1) summary
    cd17380
    Location:42377
    MFS_SLC17A9_like; Solute carrier family 17 member 9 and similar proteins of the Major Facilitator Superfamily of transporters
  3. XM_006500590.5XP_006500653.1  voltage-gated purine nucleotide uniporter SLC17A9 isoform X1

    See identical proteins and their annotated locations for XP_006500653.1

    Conserved Domains (1) summary
    cd17380
    Location:42377
    MFS_SLC17A9_like; Solute carrier family 17 member 9 and similar proteins of the Major Facilitator Superfamily of transporters

RNA

  1. XR_375393.5 RNA Sequence