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Tuba3a tubulin, alpha 3A [ Mus musculus (house mouse) ]

Gene ID: 22144, updated on 27-Feb-2024


Official Symbol
Tuba3aprovided by MGI
Official Full Name
tubulin, alpha 3Aprovided by MGI
Primary source
See related
Ensembl:ENSMUSG00000067702 AllianceGenome:MGI:1095406
Gene type
protein coding
RefSeq status
Mus musculus
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
M[a]3; Tuba3
Predicted to enable GTP binding activity. Predicted to be a structural constituent of cytoskeleton. Predicted to be involved in microtubule cytoskeleton organization and mitotic cell cycle. Located in ciliary basal body and microtubule. [provided by Alliance of Genome Resources, Apr 2022]
Restricted expression toward testis adult (RPKM 1237.0) See more
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Genomic context

See Tuba3a in Genome Data Viewer
6 F3; 6 59.32 cM
Exon count:
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (125255233..125263044, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (125278270..125286081, complement)

Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930417O13 gene Neighboring gene predicted gene, 24175 Neighboring gene CapStarr-seq enhancer MGSCv37_chr6:125215268-125215572 Neighboring gene STARR-seq mESC enhancer starr_17336 Neighboring gene lymphotoxin B receptor Neighboring gene sodium channel, nonvoltage-gated 1 alpha Neighboring gene STARR-seq mESC enhancer starr_17338 Neighboring gene tumor necrosis factor receptor superfamily, member 1a

Genomic regions, transcripts, and products


  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a



Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 
  • Endonuclease-mediated (5)  1 citation


Products Interactant Other Gene Complex Source Pubs Description

General gene information


Clone Names

  • MGC107295

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables GTP binding IBA
Inferred from Biological aspect of Ancestor
more info
enables molecular_function ND
No biological Data available
more info
enables structural constituent of cytoskeleton IBA
Inferred from Biological aspect of Ancestor
more info
Process Evidence Code Pubs
acts_upstream_of_or_within male germ-line stem cell population maintenance IMP
Inferred from Mutant Phenotype
more info
involved_in microtubule cytoskeleton organization IBA
Inferred from Biological aspect of Ancestor
more info
involved_in mitotic cell cycle IBA
Inferred from Biological aspect of Ancestor
more info
Component Evidence Code Pubs
located_in ciliary basal body IDA
Inferred from Direct Assay
more info
located_in cilium IDA
Inferred from Direct Assay
more info
is_active_in cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
is_active_in microtubule IBA
Inferred from Biological aspect of Ancestor
more info
located_in microtubule IDA
Inferred from Direct Assay
more info
located_in microtubule cytoskeleton ISO
Inferred from Sequence Orthology
more info

General protein information

Preferred Names
tubulin alpha-3 chain
alpha-tubulin 3/7
alpha-tubulin isotype M-alpha-3/7
tubulin, alpha 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009446.3NP_033472.1  tubulin alpha-3 chain

    See identical proteins and their annotated locations for NP_033472.1

    Status: VALIDATED

    Source sequence(s)
    AK132775, AV259496, DV656074
    Consensus CDS
    Q3TIZ0, Q5FW91
    ENSMUSP00000085580.6, ENSMUST00000088246.6
    Conserved Domains (1) summary
    PTZ00335; tubulin alpha chain; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J


  1. NC_000072.7 Reference GRCm39 C57BL/6J

    125255233..125263044 complement
    GenBank, FASTA, Sequence Viewer (Graphics)