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TIGD3 tigger transposable element derived 3 [ Homo sapiens (human) ]

Gene ID: 220359, updated on 23-Nov-2021

Summary

Official Symbol
TIGD3provided by HGNC
Official Full Name
tigger transposable element derived 3provided by HGNC
Primary source
HGNC:HGNC:18334
See related
Ensembl:ENSG00000173825 MIM:619084
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Summary
The protein encoded by this gene belongs to the tigger subfamily of the pogo superfamily of DNA-mediated transposons in humans. These proteins are related to DNA transposons found in fungi and nematodes, and more distantly to the Tc1 and mariner transposases. They are also very similar to the major mammalian centromere protein B. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]
Expression
Broad expression in testis (RPKM 2.0), small intestine (RPKM 1.1) and 14 other tissues See more
Orthologs
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Genomic context

See TIGD3 in Genome Data Viewer
Location:
11q13.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20211119 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (65354751..65357613)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (65122222..65125084)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene CDC42 effector protein 2 Neighboring gene double PHD fingers 2 Neighboring gene solute carrier family 25 member 45 Neighboring gene Sharpr-MPRA regulatory region 983 Neighboring gene FERM domain containing 8

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables DNA binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
is_active_in nucleus IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
tigger transposable element-derived protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145719.3NP_663771.1  tigger transposable element-derived protein 3

    See identical proteins and their annotated locations for NP_663771.1

    Status: REVIEWED

    Source sequence(s)
    AP000944, BC074862, BU741546, DR002049
    Consensus CDS
    CCDS8101.1
    UniProtKB/Swiss-Prot
    Q6B0B8
    Related
    ENSP00000308354.5, ENST00000309880.6
    Conserved Domains (3) summary
    pfam03221
    Location:76133
    HTH_Tnp_Tc5; Tc5 transposase DNA-binding domain
    cl21459
    Location:657
    HTH; Helix-turn-helix domains
    cl21549
    Location:193360
    rve; Integrase core domain

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    65354751..65357613
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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