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PPP1R32 protein phosphatase 1 regulatory subunit 32 [ Homo sapiens (human) ]

Gene ID: 220004, updated on 1-Jun-2020

Summary

Official Symbol
PPP1R32provided by HGNC
Official Full Name
protein phosphatase 1 regulatory subunit 32provided by HGNC
Primary source
HGNC:HGNC:28869
See related
Ensembl:ENSG00000162148
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
IIIG9; C11orf66
Expression
Biased expression in testis (RPKM 29.1) and lung (RPKM 2.8) See more
Orthologs

Genomic context

See PPP1R32 in Genome Data Viewer
Location:
11q12.2
Exon count:
14
Annotation release Status Assembly Chr Location
109.20200522 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (61481120..61490928)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (61248585..61258400)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene cleavage and polyadenylation specific factor 7 Neighboring gene succinate dehydrogenase complex assembly factor 2 Neighboring gene RNA, 7SL, cytoplasmic 23, pseudogene Neighboring gene uncharacterized LOC105369329 Neighboring gene microRNA 4488

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Potential readthrough

Included gene: SDHAF2

Homology

Clone Names

  • FLJ32771

Gene Ontology Provided by GOA

Function Evidence Code Pubs
phosphatase binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
phosphatase binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 

General protein information

Preferred Names
protein phosphatase 1 regulatory subunit 32

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001170753.2NP_001164224.1  protein phosphatase 1 regulatory subunit 32 isoform 2

    See identical proteins and their annotated locations for NP_001164224.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1.
    Source sequence(s)
    BC043246, BC053995
    Consensus CDS
    CCDS53641.1
    UniProtKB/Swiss-Prot
    Q7Z5V6
    Related
    ENSP00000391560.2, ENST00000432063.6
    Conserved Domains (1) summary
    pfam15691
    Location:2396
    PPP1R32; Protein phosphatase 1 regulatory subunit 32
  2. NM_145017.3NP_659454.2  protein phosphatase 1 regulatory subunit 32 isoform 1

    See identical proteins and their annotated locations for NP_659454.2

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
    Source sequence(s)
    BC053995, BI561157
    Consensus CDS
    CCDS8008.1
    UniProtKB/Swiss-Prot
    Q7Z5V6
    UniProtKB/TrEMBL
    G3F4G3
    Related
    ENSP00000344140.2, ENST00000338608.7
    Conserved Domains (1) summary
    pfam15691
    Location:2416
    PPP1R32; Protein phosphatase 1 regulatory subunit 32

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    61481120..61490928
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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