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FAM241B family with sequence similarity 241 member B [ Homo sapiens (human) ]

Gene ID: 219738, updated on 9-Jul-2019

Summary

Official Symbol
FAM241Bprovided by HGNC
Official Full Name
family with sequence similarity 241 member Bprovided by HGNC
Primary source
HGNC:HGNC:23519
See related
Ensembl:ENSG00000171224
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C10orf35
Expression
Broad expression in brain (RPKM 5.1), testis (RPKM 3.6) and 24 other tissues See more
Orthologs

Genomic context

See FAM241B in Genome Data Viewer
Location:
10q22.1
Exon count:
6
Annotation release Status Assembly Chr Location
109.20190607 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (69630241..69633599)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (71390003..71393355)

Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene MT-ND2 pseudogene 15 Neighboring gene MT-ND1 pseudogene 20 Neighboring gene long intergenic non-protein coding RNA 2651 Neighboring gene ribosomal protein L5 pseudogene 26

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility.
NHGRI GWA Catalog

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Component Evidence Code Pubs
integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
intracellular membrane-bounded organelle IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
uncharacterized protein FAM241B
Names
uncharacterized protein C10orf35

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_145306.3NP_660349.1  uncharacterized protein FAM241B

    See identical proteins and their annotated locations for NP_660349.1

    Status: VALIDATED

    Source sequence(s)
    BC013587, CK903062, DB339258, DB465414
    Consensus CDS
    CCDS7295.1
    UniProtKB/Swiss-Prot
    Q96D05
    UniProtKB/TrEMBL
    A0A024QZL0
    Related
    ENSP00000362376.4, ENST00000373279.6
    Conserved Domains (1) summary
    pfam15378
    Location:6392
    DUF4605; Domain of unknown function (DUF4605)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

    Range
    69630241..69633599
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005269608.3XP_005269665.1  uncharacterized protein FAM241B isoform X2

    See identical proteins and their annotated locations for XP_005269665.1

    UniProtKB/Swiss-Prot
    Q96D05
    UniProtKB/TrEMBL
    A0A024QZL0
    Conserved Domains (1) summary
    pfam15378
    Location:6392
    DUF4605; Domain of unknown function (DUF4605)
  2. XM_005269606.2XP_005269663.1  uncharacterized protein FAM241B isoform X1

    UniProtKB/Swiss-Prot
    Q96D05
    Conserved Domains (1) summary
    pfam15378
    Location:105134
    DUF4605; Domain of unknown function (DUF4605)
  3. XM_017015836.1XP_016871325.1  uncharacterized protein FAM241B isoform X2

    UniProtKB/Swiss-Prot
    Q96D05
    UniProtKB/TrEMBL
    A0A024QZL0
    Conserved Domains (1) summary
    pfam15378
    Location:6392
    DUF4605; Domain of unknown function (DUF4605)
  4. XM_011539455.2XP_011537757.1  uncharacterized protein FAM241B isoform X2

    See identical proteins and their annotated locations for XP_011537757.1

    UniProtKB/Swiss-Prot
    Q96D05
    UniProtKB/TrEMBL
    A0A024QZL0
    Conserved Domains (1) summary
    pfam15378
    Location:6392
    DUF4605; Domain of unknown function (DUF4605)
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