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LRRC55 leucine rich repeat containing 55 [ Homo sapiens (human) ]

Gene ID: 219527, updated on 21-Dec-2019

Summary

Official Symbol
LRRC55provided by HGNC
Official Full Name
leucine rich repeat containing 55provided by HGNC
Primary source
HGNC:HGNC:32324
See related
Ensembl:ENSG00000183908 MIM:615213
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Expression
Broad expression in brain (RPKM 2.8), lymph node (RPKM 1.5) and 14 other tissues See more
Orthologs

Genomic context

See LRRC55 in Genome Data Viewer
Location:
11q12.1
Exon count:
2
Annotation release Status Assembly Chr Location
109.20191205 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (57181953..57191717)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (56949221..56959188)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105369309 Neighboring gene olfactory receptor family 5 subfamily AO member 1 pseudogene Neighboring gene olfactory receptor family 5 subfamily BP member 1 pseudogene Neighboring gene uncharacterized LOC107984364 Neighboring gene apelin receptor

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

General gene information

Markers

Homology

Clone Names

  • FLJ13339, FLJ45686, DKFZp667D0425

Gene Ontology Provided by GOA

Function Evidence Code Pubs
ion channel binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ion channel binding IPI
Inferred from Physical Interaction
more info
PubMed 
potassium channel activator activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
potassium channel activator activity IDA
Inferred from Direct Assay
more info
PubMed 
voltage-gated potassium channel activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
voltage-gated potassium channel activity IDA
Inferred from Direct Assay
more info
PubMed 
Component Evidence Code Pubs
integral component of plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
voltage-gated potassium channel complex IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
voltage-gated potassium channel complex IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
leucine-rich repeat-containing protein 55
Names
BK channel auxiliary gamma subunit LRRC55
BK channel auxilliary gamma snit LRRC55

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001005210.4NP_001005210.2  leucine-rich repeat-containing protein 55 precursor

    Status: VALIDATED

    Source sequence(s)
    AK023401, AK127591, AP001786
    Consensus CDS
    CCDS31539.1
    Related
    ENSP00000419542.2, ENST00000497933.3
    Conserved Domains (4) summary
    sd00033
    Location:4766
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:90148
    LRR_8; Leucine rich repeat
    cl15307
    Location:196247
    TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain
    cl26793
    Location:47201
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    57181953..57191717
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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