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OR4S2 olfactory receptor family 4 subfamily S member 2 [ Homo sapiens (human) ]

Gene ID: 219431, updated on 11-Jun-2021

Summary

Official Symbol
OR4S2provided by HGNC
Official Full Name
olfactory receptor family 4 subfamily S member 2provided by HGNC
Primary source
HGNC:HGNC:15183
See related
Ensembl:ENSG00000174982
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
OR4S2P; OST725; OR11-137
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See OR4S2 in Genome Data Viewer
Location:
11q11
Exon count:
2
Annotation release Status Assembly Chr Location
109.20210514 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (55648327..55652854)
105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (55415803..55420330)

Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 4 subfamily C member 11 Neighboring gene olfactory receptor family 4 subfamily P member 4 Neighboring gene olfactory receptor family 4 subfamily C member 6 Neighboring gene olfactory receptor family 4 subfamily V member 1 pseudogene

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Homology

Gene Ontology Provided by GOA

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
located_in integral component of membrane IEA
Inferred from Electronic Annotation
more info
 
located_in plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
olfactory receptor 4S2
Names
olfactory receptor OR11-137
olfactory receptor, family 4, subfamily S, member 2 pseudogene

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001004059.3NP_001004059.2  olfactory receptor 4S2

    See identical proteins and their annotated locations for NP_001004059.2

    Status: VALIDATED

    Source sequence(s)
    AP006437
    Consensus CDS
    CCDS31505.1
    UniProtKB/Swiss-Prot
    Q8NH73
    UniProtKB/TrEMBL
    A0A126GVG1
    Related
    ENSP00000493389.1, ENST00000641692.1
    Conserved Domains (2) summary
    pfam00001
    Location:54285
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:56299
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p13 Primary Assembly

Genomic

  1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

    Range
    55648327..55652854
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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