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Lhfpl2 lipoma HMGIC fusion partner-like 2 [ Mus musculus (house mouse) ]

Gene ID: 218454, updated on 5-Mar-2024

Summary

Official Symbol
Lhfpl2provided by MGI
Official Full Name
lipoma HMGIC fusion partner-like 2provided by MGI
Primary source
MGI:MGI:2145236
See related
Ensembl:ENSMUSG00000045312 AllianceGenome:MGI:2145236
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
vgim; mKIAA0206; 6030465B15
Summary
Involved in development of primary female sexual characteristics; development of primary male sexual characteristics; and positive regulation of fertilization. Predicted to be integral component of membrane. Predicted to be active in membrane. Is expressed in several structures, including hemolymphoid system gland; liver; lung; reproductive system; and tail unsegmented mesenchyme. Orthologous to human LHFPL2 (LHFPL tetraspan subfamily member 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in subcutaneous fat pad adult (RPKM 19.7), limb E14.5 (RPKM 15.8) and 23 other tissues See more
Orthologs
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Genomic context

See Lhfpl2 in Genome Data Viewer
Location:
13 C3; 13 49.03 cM
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (94193659..94331918)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (94057152..94195410)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_35297 Neighboring gene predicted gene, 24737 Neighboring gene STARR-seq mESC enhancer starr_35299 Neighboring gene STARR-seq mESC enhancer starr_35300 Neighboring gene cytochrome c, pseudogene 3 Neighboring gene predicted gene, 57596 Neighboring gene secretory carrier membrane protein 1 Neighboring gene STARR-seq mESC enhancer starr_35303 Neighboring gene predicted gene, 32089

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Spontaneous (1) 
  • Targeted (1) 
  • Endonuclease-mediated (2) 

Pathways from PubChem

General gene information

Markers

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables molecular_function ND
No biological Data available
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
LHFPL tetraspan subfamily member 2 protein
Names
lipoma HMGIC fusion partner-like 2 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172589.2NP_766177.1  LHFPL tetraspan subfamily member 2 protein

    See identical proteins and their annotated locations for NP_766177.1

    Status: PROVISIONAL

    Source sequence(s)
    AK087506
    Consensus CDS
    CCDS26692.1
    UniProtKB/Swiss-Prot
    Q8BGA2
    Related
    ENSMUSP00000062239.2, ENSMUST00000054274.8
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    94193659..94331918
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030247231.2XP_030103091.1  LHFPL tetraspan subfamily member 2 protein isoform X2

  2. XM_011244639.4XP_011242941.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    See identical proteins and their annotated locations for XP_011242941.1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  3. XM_036158012.1XP_036013905.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  4. XM_011244640.3XP_011242942.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    See identical proteins and their annotated locations for XP_011242942.1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  5. XM_036158013.1XP_036013906.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  6. XM_036158014.1XP_036013907.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  7. XM_011244641.4XP_011242943.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    See identical proteins and their annotated locations for XP_011242943.1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  8. XM_011244642.4XP_011242944.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    See identical proteins and their annotated locations for XP_011242944.1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family
  9. XM_011244643.4XP_011242945.1  LHFPL tetraspan subfamily member 2 protein isoform X1

    See identical proteins and their annotated locations for XP_011242945.1

    UniProtKB/Swiss-Prot
    Q8BGA2
    Related
    ENSMUSP00000113468.2, ENSMUST00000121618.2
    Conserved Domains (1) summary
    cl21598
    Location:9198
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family