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Mboat1 membrane bound O-acyltransferase domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 218121, updated on 26-Sep-2022

Summary

Official Symbol
Mboat1provided by MGI
Official Full Name
membrane bound O-acyltransferase domain containing 1provided by MGI
Primary source
MGI:MGI:2387184
See related
Ensembl:ENSMUSG00000038732 AllianceGenome:MGI:2387184
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
Oact1; LPEAT1; Moact1; 9130215M02Rik
Summary
Enables 1-acylglycerophosphoethanolamine O-acyltransferase activity. Involved in phosphatidylethanolamine acyl-chain remodeling; phospholipid biosynthetic process; and regulation of neuron projection development. Located in endoplasmic reticulum membrane. Is expressed in several structures, including gut; integumental system; nervous system; respiratory system; and urinary system. Orthologous to human MBOAT1 (membrane bound O-acyltransferase domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Biased expression in colon adult (RPKM 26.9), stomach adult (RPKM 19.8) and 11 other tissues See more
Orthologs
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Genomic context

See Mboat1 in Genome Data Viewer
Location:
13; 13 A3.2
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (30320295..30430677)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (30136451..30246694)

Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene E2F transcription factor 3 Neighboring gene predicted gene, 40860 Neighboring gene predicted gene, 23206 Neighboring gene predicted gene, 40869 Neighboring gene non-POU-domain-containing, octamer binding protein pseudogene Neighboring gene predicted gene, 40863 Neighboring gene predicted gene, 53782 Neighboring gene angiotensin II receptor, type 1a Neighboring gene ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC38410

Gene Ontology Provided by MGI

Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
located_in endoplasmic reticulum membrane IDA
Inferred from Direct Assay
more info
PubMed 
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 

General protein information

Preferred Names
lysophospholipid acyltransferase 1
Names
1-acylglycerophosphocholine O-acyltransferase
1-acylglycerophosphoethanolamine O-acyltransferase
1-acylglycerophosphoethanolamine O-acyltransferase MBOAT1
1-acylglycerophosphoserine O-acyltransferase
1-acylglycerophosphoserine O-acyltransferase MBOAT1
LPE acyltransferase 1
LPEAT
LPLAT 1
LPSAT
O-acyltransferase (membrane bound) domain containing 1
O-acyltransferase domain-containing protein 1
lyso-PE acyltransferase
lyso-PS acyltransferase
lysophosphatidylethanolamine acyltransferase
lysophosphatidylethanolamine acyltransferase 1
lysophosphatidylserine acyltransferase
membrane bound O-acyl transferase family, member 1
membrane-bound O-acyltransferase domain-containing protein 1
NP_705774.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_153546.4NP_705774.1  lysophospholipid acyltransferase 1

    See identical proteins and their annotated locations for NP_705774.1

    Status: PROVISIONAL

    Source sequence(s)
    AL450321, AL645749
    Consensus CDS
    CCDS26414.1
    UniProtKB/Swiss-Prot
    Q8BH98, Q8R3T2
    Related
    ENSMUSP00000045441.9, ENSMUST00000047311.16
    Conserved Domains (1) summary
    cl00738
    Location:21458
    MBOAT; MBOAT, membrane-bound O-acyltransferase family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000079.7 Reference GRCm39 C57BL/6J

    Range
    30320295..30430677
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

RNA

  1. XR_004938018.1 RNA Sequence