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Rundc1 RUN domain containing 1 [ Mus musculus (house mouse) ]

Gene ID: 217201, updated on 2-Nov-2024

Summary

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Official Symbol
Rundc1provided by MGI
Official Full Name
RUN domain containing 1provided by MGI
Primary source
MGI:MGI:2144506
See related
Ensembl:ENSMUSG00000035007 AllianceGenome:MGI:2144506
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
D930024B17
Summary
Acts upstream of or within in utero embryonic development. Is expressed in central nervous system and retina. Orthologous to human RUNDC1 (RUN domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 12.9), colon adult (RPKM 12.1) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Rundc1 in Genome Data Viewer
Location:
11 D; 11 65.0 cM
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (101315910..101326492)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (101425085..101435666)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene alanyl-tRNA synthetase domain containing 1 Neighboring gene prostaglandin E synthase 3 like Neighboring gene microRNA 6929 Neighboring gene STARR-positive B cell enhancer ABC_E596 Neighboring gene STARR-positive B cell enhancer ABC_E1431 Neighboring gene ribosomal protein L27 Neighboring gene STARR-positive B cell enhancer ABC_E7067 Neighboring gene STARR-seq mESC enhancer starr_30763 Neighboring gene interferon-induced protein 35

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Knockout mice with pituitary malformations help identify human cases of hypopituitarism. Martinez-Mayer J, et al. Genome Med, 2024 May 31. PMID 38822427, Free PMC Article
  2. A staging system for correct phenotype interpretation of mouse embryos harvested on embryonic day 14 (E14.5). Geyer SH, et al. J Anat, 2017 May. PMID 28185240, Free PMC Article
  3. Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice. Wilson R, et al. Wellcome Open Res, 2016. PMID 27996060, Free PMC Article
  4. Placentation defects are highly prevalent in embryonic lethal mouse mutants. Perez-Garcia V, et al. Nature, 2018 Mar 22. PMID 29539633, Free PMC Article
  5. Mouse screen reveals multiple new genes underlying mouse and human hearing loss. Ingham NJ, et al. PLoS Biol, 2019 Apr. PMID 30973865, Free PMC Article

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC141375, MGC141376

Gene Ontology Provided by MGI

Process Evidence Code Pubs
acts_upstream_of_or_within in utero embryonic development IMP
Inferred from Mutant Phenotype
more info
 PubMed 

General protein information

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Preferred Names
RUN domain-containing protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_172566.4 → NP_766154.2  RUN domain-containing protein 1

    See identical proteins and their annotated locations for NP_766154.2

    Status: VALIDATED

    Source sequence(s)
    AK086362, AW125546, BC119592
    Consensus CDS
    CCDS25469.1
    UniProtKB/Swiss-Prot
    Q0VDN6, Q0VDN7, Q3U072, Q8C3C0
    Related
    ENSMUSP00000042151.6, ENSMUST00000040561.6
    Conserved Domains (1) summary
    cl02689
    Location:431 → 582
    RUN; RUN domain

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    101315910..101326492
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006533035.5 → XP_006533098.1  RUN domain-containing protein 1 isoform X1

    Conserved Domains (2) summary
    TIGR04523
    Location:167 → 291
    Mplasa_alph_rch; helix-rich Mycoplasma protein
    cl02689
    Location:433 → 584
    RUN; RUN domain
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q0VDN7.1 GenPept UniProtKB/Swiss-Prot:Q0VDN7

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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