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Mmgt2 membrane magnesium transporter 2 [ Mus musculus (house mouse) ]

Gene ID: 216829, updated on 30-Apr-2024

Summary

Official Symbol
Mmgt2provided by MGI
Official Full Name
membrane magnesium transporter 2provided by MGI
Primary source
MGI:MGI:2448491
See related
Ensembl:ENSMUSG00000048497 AllianceGenome:MGI:2448491
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Enables metal ion transmembrane transporter activity. Acts upstream of or within metal ion transport. Located in Golgi apparatus; early endosome; and plasma membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human MMGT1 (membrane magnesium transporter 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in bladder adult (RPKM 10.2), limb E14.5 (RPKM 7.6) and 27 other tissues See more
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Genomic context

See Mmgt2 in Genome Data Viewer
Location:
11 B2; 11 38.56 cM
Exon count:
4
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (62538999..62557185)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (62648180..62666359)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2410006H16 gene Neighboring gene small nucleolar RNA, C/D box 65 Neighboring gene leucine rich repeat containing 75A Neighboring gene leucine rich repeat containing 75A, opposite strand 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:62462281-62462390 Neighboring gene zinc finger protein 287 Neighboring gene nuclear encoded tRNA trytophan 8 (anticodon CCA)

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC36859

Gene Ontology Provided by MGI

Component Evidence Code Pubs
part_of EMC complex IBA
Inferred from Biological aspect of Ancestor
more info
 
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in Golgi apparatus IDA
Inferred from Direct Assay
more info
PubMed 
located_in Golgi membrane TAS
Traceable Author Statement
more info
 
is_active_in early endosome IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in early endosome IDA
Inferred from Direct Assay
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 
is_active_in plasma membrane IBA
Inferred from Biological aspect of Ancestor
more info
 
located_in plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
membrane magnesium transporter 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_175002.2NP_778167.1  membrane magnesium transporter 2

    See identical proteins and their annotated locations for NP_778167.1

    Status: VALIDATED

    Source sequence(s)
    AK131977, AL596181, BB871237
    Consensus CDS
    CCDS36179.1
    UniProtKB/Swiss-Prot
    Q8R3L0
    Related
    ENSMUSP00000128697.2, ENSMUST00000155759.3
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    62538999..62557185
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011248909.3XP_011247211.2  membrane magnesium transporter 2 isoform X1

  2. XM_036156560.1XP_036012453.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  3. XM_036156556.1XP_036012449.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  4. XM_036156558.1XP_036012451.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Related
    ENSMUSP00000128669.2, ENSMUST00000129162.3
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  5. XM_036156557.1XP_036012450.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  6. XM_006532870.2XP_006532933.1  membrane magnesium transporter 2 isoform X2

    See identical proteins and their annotated locations for XP_006532933.1

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  7. XM_036156559.1XP_036012452.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter
  8. XM_036156555.1XP_036012448.1  membrane magnesium transporter 2 isoform X2

    UniProtKB/Swiss-Prot
    Q8R3L0
    Conserved Domains (1) summary
    pfam10270
    Location:1290
    MMgT; Membrane magnesium transporter