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Ehbp1 EH domain binding protein 1 [ Mus musculus (house mouse) ]

Gene ID: 216565, updated on 30-Apr-2024

Summary

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Official Symbol
Ehbp1provided by MGI
Official Full Name
EH domain binding protein 1provided by MGI
Primary source
MGI:MGI:2667252
See related
Ensembl:ENSMUSG00000042302 AllianceGenome:MGI:2667252
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
NACSIN; Flj21950
Summary
Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within endocytosis and protein transport. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be part of filamentous actin. Predicted to be active in microtubule organizing center. Orthologous to human EHBP1 (EH domain binding protein 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Broad expression in CNS E18 (RPKM 12.7), CNS E14 (RPKM 11.7) and 19 other tissues See more
Orthologs
human all
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Genomic context

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See Ehbp1 in Genome Data Viewer
Location:
11 A3.2; 11 14.1 cM
Exon count:
27
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (21955825..22237086, complement)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (22005825..22287083, complement)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_28856 Neighboring gene ferritin light chain 1 pseudogene Neighboring gene predicted gene, 53673 Neighboring gene orthodenticle homeobox 1 Neighboring gene predicted gene, 51938 Neighboring gene STARR-seq mESC enhancer starr_28857 Neighboring gene STARR-positive B cell enhancer ABC_E584 Neighboring gene predicted gene, 53674 Neighboring gene DnaJ (Hsp40) homolog, subfamily A, member 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_28858 Neighboring gene STARR-seq mESC enhancer starr_28859 Neighboring gene ribosomal protein SA, pseudogene 3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton. Guilherme A, et al. J Biol Chem, 2004 Mar 12. PMID 14676205
  2. Genetic predisposition to tinnitus in the UK Biobank population. Urbanek ME, et al. Sci Rep, 2021 Sep 13. PMID 34518561, Free PMC Article
  3. EHBP1L1 coordinates Rab8 and Bin1 to regulate apical-directed transport in polarized epithelial cells. Nakajo A, et al. J Cell Biol, 2016 Feb 1. PMID 26833786, Free PMC Article
  4. Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes. Guilherme A, et al. J Biol Chem, 2004 Sep 17. PMID 15247266
  5. Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14. Fuchs S, et al. BMC Genet, 2002 Aug 13. PMID 12174196, Free PMC Article

See all (27) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. EHD1 and EHBP1, but not EHD2, are required for perinuclear localization of GLUT4 and reveal that loss of EHBP1 disrupts insulin-regulated GLUT4 recycling in cultured adipocytes.
    Title: Role of EHD1 and EHBP1 in perinuclear sorting and insulin-regulated GLUT4 recycling in 3T3-L1 adipocytes.
  2. EHBP1 is an EH domain binding protein that, along with EHD2, has a role in coupling endocytosis to the actin cytoskeleton [EHBP1]
    Title: EHD2 and the novel EH domain binding protein EHBP1 couple endocytosis to the actin cytoskeleton.
Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (3) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables protein binding IPI
Inferred from Physical Interaction
more info
 PubMed 
Process Evidence Code Pubs
acts_upstream_of_or_within endocytosis IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytosol ISO
Inferred from Sequence Orthology
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in nucleoplasm ISO
Inferred from Sequence Orthology
more info
  
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
EH domain-binding protein 1
Names
DNA sequence AF424697

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001252515.1 → NP_001239444.1  EH domain-binding protein 1 isoform 1

    See identical proteins and their annotated locations for NP_001239444.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longer isoform (1).
    Source sequence(s)
    AF424697, AK173055, BC037023
    Consensus CDS
    CCDS56762.1
    UniProtKB/Swiss-Prot
    E9QMJ9, Q5SQK3, Q69ZW3, Q91ZJ6
    Related
    ENSMUSP00000105191.3, ENSMUST00000109563.9
    Conserved Domains (3) summary
    pfam00307
    Location:457 → 553
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1070 → 1210
    DUF3585; Protein of unknown function (DUF3585)

  2. NM_153078.4 → NP_694718.4  EH domain-binding protein 1 isoform 2

    See identical proteins and their annotated locations for NP_694718.4

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) has an alternate splice site in the coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
    Source sequence(s)
    AF424697, AK173055, BC037023
    Consensus CDS
    CCDS24469.1
    UniProtKB/Swiss-Prot
    Q69ZW3
    Related
    ENSMUSP00000136697.2, ENSMUST00000180360.8
    Conserved Domains (4) summary
    COG0419
    Location:872 → 1202
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1052 → 1180
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    21955825..22237086 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036156528.1 → XP_036012421.1  EH domain-binding protein 1 isoform X14

    Related
    ENSMUSP00000037489.5, ENSMUST00000045167.11
    Conserved Domains (4) summary
    COG0419
    Location:872 → 1202
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1052 → 1180
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  2. XM_011243681.4 → XP_011241983.1  EH domain-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011241983.1

    Conserved Domains (4) summary
    COG0419
    Location:920 → 1253
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1100 → 1236
    DUF3585; Protein of unknown function (DUF3585)

  3. XM_011243684.4 → XP_011241986.1  EH domain-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011241986.1

    Conserved Domains (4) summary
    COG0419
    Location:920 → 1253
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1100 → 1236
    DUF3585; Protein of unknown function (DUF3585)

  4. XM_030245788.2 → XP_030101648.1  EH domain-binding protein 1 isoform X7

    Conserved Domains (4) summary
    COG0419
    Location:885 → 1218
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1068 → 1196
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:419 → 525
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  5. XM_017314437.3 → XP_017169926.1  EH domain-binding protein 1 isoform X5

    Conserved Domains (4) summary
    COG0419
    Location:895 → 1228
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1078 → 1206
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  6. XM_011243683.4 → XP_011241985.1  EH domain-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011241985.1

    Conserved Domains (4) summary
    COG0419
    Location:920 → 1253
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1100 → 1236
    DUF3585; Protein of unknown function (DUF3585)

  7. XM_036156526.1 → XP_036012419.1  EH domain-binding protein 1 isoform X7

    Conserved Domains (4) summary
    COG0419
    Location:885 → 1218
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1068 → 1196
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:419 → 525
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  8. XM_036156530.1 → XP_036012423.1  EH domain-binding protein 1 isoform X21

    Conserved Domains (4) summary
    COG1196
    Location:900 → 1186
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1035 → 1163
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  9. XM_036156524.1 → XP_036012417.1  EH domain-binding protein 1 isoform X5

    Conserved Domains (4) summary
    COG0419
    Location:895 → 1228
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1078 → 1206
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  10. XM_036156523.1 → XP_036012416.1  EH domain-binding protein 1 isoform X3

    Conserved Domains (4) summary
    COG0419
    Location:897 → 1230
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1080 → 1208
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  11. XM_011243682.3 → XP_011241984.1  EH domain-binding protein 1 isoform X1

    See identical proteins and their annotated locations for XP_011241984.1

    Conserved Domains (4) summary
    COG0419
    Location:920 → 1253
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1100 → 1236
    DUF3585; Protein of unknown function (DUF3585)

  12. XM_036156535.1 → XP_036012428.1  EH domain-binding protein 1 isoform X30

    Conserved Domains (4) summary
    COG1196
    Location:837 → 1109
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:980 → 1108
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:394 → 500
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  13. XM_036156534.1 → XP_036012427.1  EH domain-binding protein 1 isoform X29

    Conserved Domains (4) summary
    COG1196
    Location:840 → 1135
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:984 → 1112
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:394 → 500
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  14. XM_030245791.2 → XP_030101651.1  EH domain-binding protein 1 isoform X17

    Conserved Domains (4) summary
    COG0419
    Location:860 → 1193
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:397 → 499
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1040 → 1176
    DUF3585; Protein of unknown function (DUF3585)

  15. XM_030245796.2 → XP_030101656.1  EH domain-binding protein 1 isoform X26

    Conserved Domains (4) summary
    COG1196
    Location:864 → 1159
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:422 → 524
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1005 → 1141
    DUF3585; Protein of unknown function (DUF3585)

  16. XM_036156532.1 → XP_036012425.1  EH domain-binding protein 1 isoform X27

    Conserved Domains (4) summary
    COG1196
    Location:760 → 1135
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1006 → 1134
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:419 → 525
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  17. XM_017314440.3 → XP_017169929.1  EH domain-binding protein 1 isoform X25

    Conserved Domains (4) summary
    COG1196
    Location:760 → 1138
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:422 → 524
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1006 → 1142
    DUF3585; Protein of unknown function (DUF3585)

  18. XM_011243693.4 → XP_011241995.1  EH domain-binding protein 1 isoform X15

    Conserved Domains (4) summary
    COG0419
    Location:862 → 1195
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:422 → 524
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1042 → 1178
    DUF3585; Protein of unknown function (DUF3585)

  19. XM_011243689.4 → XP_011241991.1  EH domain-binding protein 1 isoform X7

    Conserved Domains (4) summary
    COG0419
    Location:885 → 1218
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1068 → 1196
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:419 → 525
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  20. XM_036156531.1 → XP_036012424.1  EH domain-binding protein 1 isoform X22

    Conserved Domains (4) summary
    COG0419
    Location:782 → 1182
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1032 → 1160
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  21. XM_030245789.2 → XP_030101649.1  EH domain-binding protein 1 isoform X13

    Conserved Domains (4) summary
    COG0419
    Location:872 → 1205
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:432 → 534
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1052 → 1188
    DUF3585; Protein of unknown function (DUF3585)

  22. XM_011243688.4 → XP_011241990.1  EH domain-binding protein 1 isoform X5

    Conserved Domains (4) summary
    COG0419
    Location:895 → 1228
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1078 → 1206
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:429 → 535
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  23. XM_011243692.4 → XP_011241994.1  EH domain-binding protein 1 isoform X11

    Conserved Domains (4) summary
    COG0419
    Location:807 → 1209
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1056 → 1192
    DUF3585; Protein of unknown function (DUF3585)

  24. XM_030245795.2 → XP_030101655.1  EH domain-binding protein 1 isoform X24

    Conserved Domains (4) summary
    COG1196
    Location:752 → 1150
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1018 → 1154
    DUF3585; Protein of unknown function (DUF3585)

  25. XM_030245794.2 → XP_030101654.1  EH domain-binding protein 1 isoform X23

    Conserved Domains (4) summary
    COG1196
    Location:752 → 1153
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1021 → 1157
    DUF3585; Protein of unknown function (DUF3585)

  26. XM_017314438.3 → XP_017169927.1  EH domain-binding protein 1 isoform X12

    Conserved Domains (4) summary
    COG0419
    Location:807 → 1207
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1054 → 1190
    DUF3585; Protein of unknown function (DUF3585)

  27. XM_011243691.4 → XP_011241993.1  EH domain-binding protein 1 isoform X10

    Conserved Domains (4) summary
    COG0419
    Location:807 → 1210
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1057 → 1193
    DUF3585; Protein of unknown function (DUF3585)

  28. XM_030245792.2 → XP_030101652.1  EH domain-binding protein 1 isoform X20

    Conserved Domains (4) summary
    COG1196
    Location:897 → 1169
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1037 → 1173
    DUF3585; Protein of unknown function (DUF3585)

  29. XM_036156529.1 → XP_036012422.1  EH domain-binding protein 1 isoform X18

    Conserved Domains (4) summary
    COG1196
    Location:899 → 1194
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1043 → 1171
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  30. XM_036156525.1 → XP_036012418.1  EH domain-binding protein 1 isoform X6

    Conserved Domains (4) summary
    COG0419
    Location:896 → 1226
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1076 → 1204
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  31. XM_011243687.4 → XP_011241989.1  EH domain-binding protein 1 isoform X4

    Conserved Domains (4) summary
    COG0419
    Location:896 → 1229
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1076 → 1212
    DUF3585; Protein of unknown function (DUF3585)

  32. XM_017314439.3 → XP_017169928.1  EH domain-binding protein 1 isoform X19

    Conserved Domains (4) summary
    COG1196
    Location:795 → 1170
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1038 → 1174
    DUF3585; Protein of unknown function (DUF3585)

  33. XM_030245790.2 → XP_030101650.1  EH domain-binding protein 1 isoform X16

    Conserved Domains (4) summary
    COG1196
    Location:795 → 1173
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1041 → 1177
    DUF3585; Protein of unknown function (DUF3585)

  34. XM_011243686.4 → XP_011241988.1  EH domain-binding protein 1 isoform X3

    Conserved Domains (4) summary
    COG0419
    Location:897 → 1230
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1080 → 1208
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  35. XM_036156527.1 → XP_036012420.1  EH domain-binding protein 1 isoform X9

    Conserved Domains (4) summary
    COG1196
    Location:921 → 1193
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1064 → 1192
    DUF3585; Protein of unknown function (DUF3585)
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins

  36. XM_011243690.4 → XP_011241992.1  EH domain-binding protein 1 isoform X8

    Conserved Domains (4) summary
    COG1196
    Location:923 → 1218
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1064 → 1200
    DUF3585; Protein of unknown function (DUF3585)

  37. XM_011243685.4 → XP_011241987.1  EH domain-binding protein 1 isoform X2

    Conserved Domains (4) summary
    COG0419
    Location:920 → 1250
    SbcC; DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]
    pfam00307
    Location:457 → 559
    CH; Calponin homology (CH) domain
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    pfam12130
    Location:1097 → 1233
    DUF3585; Protein of unknown function (DUF3585)

  38. XM_036156533.1 → XP_036012426.1  EH domain-binding protein 1 isoform X28

    Conserved Domains (2) summary
    pfam10358
    Location:12 → 165
    NT-C2; N-terminal C2 in EEIG1 and EHBP1 proteins
    cd21254
    Location:454 → 560
    CH_EHBP1; calponin homology (CH) domain found in EH domain-binding protein 1 and similar proteins
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q69ZW3.3 GenPept UniProtKB/Swiss-Prot:Q69ZW3

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