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Rab21 RAB21, member RAS oncogene family [ Mus musculus (house mouse) ]

Gene ID: 216344, updated on 31-Jan-2019

Summary

Official Symbol
Rab21provided by MGI
Official Full Name
RAB21, member RAS oncogene familyprovided by MGI
Primary source
MGI:MGI:894308
See related
Ensembl:ENSMUSG00000020132
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
9630024B22
Expression
Ubiquitous expression in heart adult (RPKM 17.5), bladder adult (RPKM 15.7) and 28 other tissues See more
Orthologs

Genomic context

See Rab21 in Genome Data Viewer
Location:
10; 10 D2
Exon count:
7
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (115289862..115315899, complement)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (114726918..114752647, complement)

Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 15 Neighboring gene predicted gene 8942 Neighboring gene transmembrane protein 19 Neighboring gene soc-2 (suppressor of clear) homolog pseudogene Neighboring gene THAP domain containing, apoptosis associated protein 2 Neighboring gene predicted gene, 46180

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Targeted (2) 

Pathways from BioSystems

General gene information

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
GDP binding ISO
Inferred from Sequence Orthology
more info
 
GTP binding ISO
Inferred from Sequence Orthology
more info
 
GTPase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GTPase activity ISO
Inferred from Sequence Orthology
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
Rab protein signal transduction IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
anterograde axonal transport ISO
Inferred from Sequence Orthology
more info
 
intracellular protein transport IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
positive regulation of dendrite morphogenesis IMP
Inferred from Mutant Phenotype
more info
PubMed 
positive regulation of early endosome to late endosome transport ISO
Inferred from Sequence Orthology
more info
 
positive regulation of receptor-mediated endocytosis ISO
Inferred from Sequence Orthology
more info
 
protein transport IEA
Inferred from Electronic Annotation
more info
 
regulation of axon extension ISO
Inferred from Sequence Orthology
more info
 
regulation of exocytosis ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 
Golgi cisterna membrane ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic side of early endosome membrane ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic side of plasma membrane ISO
Inferred from Sequence Orthology
more info
 
cytoplasmic vesicle IEA
Inferred from Electronic Annotation
more info
 
early endosome IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 
endosome ISO
Inferred from Sequence Orthology
more info
 
membrane IEA
Inferred from Electronic Annotation
more info
 
neuron projection IDA
Inferred from Direct Assay
more info
PubMed 
neuron projection ISO
Inferred from Sequence Orthology
more info
 
synapse ISO
Inferred from Sequence Orthology
more info
 
trans-Golgi network ISO
Inferred from Sequence Orthology
more info
 
vesicle membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
ras-related protein Rab-21
Names
rab-12

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_024454.1NP_077774.1  ras-related protein Rab-21

    See identical proteins and their annotated locations for NP_077774.1

    Status: PROVISIONAL

    Source sequence(s)
    BC055042
    Consensus CDS
    CCDS24177.1
    UniProtKB/Swiss-Prot
    P35282
    UniProtKB/TrEMBL
    Q0PD35
    Related
    ENSMUSP00000020343.7, ENSMUST00000020343.8
    Conserved Domains (2) summary
    cd04123
    Location:18179
    Rab21; Rab GTPase family 21 (Rab21)
    pfam00071
    Location:19180
    Ras; Ras family

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

    Range
    115289862..115315899 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006513537.3XP_006513600.1  ras-related protein Rab-21 isoform X1

    See identical proteins and their annotated locations for XP_006513600.1

    Conserved Domains (1) summary
    cl21455
    Location:18110
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
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