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Serpinb9 serine (or cysteine) peptidase inhibitor, clade B, member 9 [ Mus musculus (house mouse) ]

Gene ID: 20723, updated on 3-Oct-2018

Summary

Official Symbol
Serpinb9provided by MGI
Official Full Name
serine (or cysteine) peptidase inhibitor, clade B, member 9provided by MGI
Primary source
MGI:MGI:106603
See related
Ensembl:ENSMUSG00000045827 Vega:OTTMUSG00000000696
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as
PI9; CAP3; PI-9; Spi6; CAP-3; BB283241; ovalbumin
Expression
Broad expression in lung adult (RPKM 6.6), placenta adult (RPKM 6.0) and 21 other tissues See more

Genomic context

See Serpinb9 in Genome Data Viewer
Location:
13 A3.2; 13 13.79 cM
Exon count:
12
Annotation release Status Assembly Chr Location
106 current GRCm38.p4 (GCF_000001635.24) 13 NC_000079.6 (32997061..33017955)
Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (33096410..33109824)

Chromosome 13 - NC_000079.6Genomic Context describing neighboring genes Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 1c Neighboring gene SCAN domain containing 3 pseudogene Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 6b Neighboring gene predicted gene, 36181 Neighboring gene serine (or cysteine) peptidase inhibitor, clade B, member 9b Neighboring gene predicted gene, 36099 Neighboring gene SCAN domain containing 3 pseudogene

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)

Pathways from BioSystems

  • Amoebiasis, organism-specific biosystem (from KEGG)
    Amoebiasis, organism-specific biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...
  • Amoebiasis, conserved biosystem (from KEGG)
    Amoebiasis, conserved biosystemEntamoeba histolytica, an extracellular protozoan parasite is a human pathogen that invades the intestinal epithelium. Infection occurs on ingestion of contaminated water and food. The pathogenesis o...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Gene Ontology Provided by MGI

Function Evidence Code Pubs
cysteine-type endopeptidase inhibitor activity involved in apoptotic process ISO
Inferred from Sequence Orthology
more info
 
protease binding ISO
Inferred from Sequence Orthology
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
serine-type endopeptidase inhibitor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
serine-type endopeptidase inhibitor activity IMP
Inferred from Mutant Phenotype
more info
PubMed 
serine-type endopeptidase inhibitor activity ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
T cell mediated cytotoxicity IMP
Inferred from Mutant Phenotype
more info
PubMed 
acute inflammatory response to antigenic stimulus IMP
Inferred from Mutant Phenotype
more info
PubMed 
defense response to bacterium IMP
Inferred from Mutant Phenotype
more info
PubMed 
immune response ISO
Inferred from Sequence Orthology
more info
 
negative regulation by symbiont of host apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of T cell apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of apoptotic process IDA
Inferred from Direct Assay
more info
PubMed 
negative regulation of apoptotic process ISO
Inferred from Sequence Orthology
more info
 
negative regulation of endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
negative regulation of endopeptidase activity ISO
Inferred from Sequence Orthology
more info
 
positive regulation of gene expression ISO
Inferred from Sequence Orthology
more info
 
protection from natural killer cell mediated cytotoxicity ISO
Inferred from Sequence Orthology
more info
 
response to bacterium ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
Golgi apparatus ISO
Inferred from Sequence Orthology
more info
 
collagen-containing extracellular matrix HDA PubMed 
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm ISO
Inferred from Sequence Orthology
more info
 
cytosol ISO
Inferred from Sequence Orthology
more info
 
extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
extracellular space ISO
Inferred from Sequence Orthology
more info
 
intracellular ISO
Inferred from Sequence Orthology
more info
 
nucleoplasm ISO
Inferred from Sequence Orthology
more info
 
nucleus ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
serine (or cysteine) proteinase inhibitor, clade B, member 9
Names
serine protease inhibitor 6

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_009256.3NP_033282.1  serine (or cysteine) proteinase inhibitor, clade B, member 9

    See identical proteins and their annotated locations for NP_033282.1

    Status: VALIDATED

    Source sequence(s)
    AK035624, AK161581
    Consensus CDS
    CCDS26431.1
    UniProtKB/TrEMBL
    O08797
    Related
    ENSMUSP00000006391.4, ENSMUST00000006391.4
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...

RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm38.p4 C57BL/6J

Genomic

  1. NC_000079.6 Reference GRCm38.p4 C57BL/6J

    Range
    32997061..33017955
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006516625.3XP_006516688.1  serine (or cysteine) proteinase inhibitor, clade B, member 9 isoform X1

    See identical proteins and their annotated locations for XP_006516688.1

    UniProtKB/TrEMBL
    O08797
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
  2. XM_006516628.3XP_006516691.1  serine (or cysteine) proteinase inhibitor, clade B, member 9 isoform X1

    See identical proteins and their annotated locations for XP_006516691.1

    UniProtKB/TrEMBL
    O08797
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
  3. XM_017315468.1XP_017170957.1  serine (or cysteine) proteinase inhibitor, clade B, member 9 isoform X1

    UniProtKB/TrEMBL
    O08797
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
  4. XM_006516626.3XP_006516689.1  serine (or cysteine) proteinase inhibitor, clade B, member 9 isoform X1

    See identical proteins and their annotated locations for XP_006516689.1

    UniProtKB/TrEMBL
    O08797
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
  5. XM_006516629.3XP_006516692.1  serine (or cysteine) proteinase inhibitor, clade B, member 9 isoform X1

    See identical proteins and their annotated locations for XP_006516692.1

    UniProtKB/TrEMBL
    O08797
    Conserved Domains (1) summary
    cl00137
    Location:4374
    SERPIN; SERine Proteinase INhibitors (serpins) exhibit conformational polymorphism shifting from native to cleaved, latent, delta, or polymorphic forms. Many serpins, such as antitrypsin and antichymotrypsin, function as serine protease inhibitors which regulate ...
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