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Sdf2 stromal cell derived factor 2 [ Mus musculus (house mouse) ]

Gene ID: 20316, updated on 2-Nov-2024

Summary

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Official Symbol
Sdf2provided by MGI
Official Full Name
stromal cell derived factor 2provided by MGI
Primary source
MGI:MGI:108019
See related
Ensembl:ENSMUSG00000002064 AllianceGenome:MGI:108019
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be part of protein folding chaperone complex. Orthologous to human SDF2 (stromal cell derived factor 2). [provided by Alliance of Genome Resources, Nov 2024]
Expression
Ubiquitous expression in ovary adult (RPKM 68.0), genital fat pad adult (RPKM 59.3) and 28 other tissues See more
Orthologs
human all
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Genomic context

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See Sdf2 in Genome Data Viewer
Location:
11 B5; 11 46.74 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78136817..78146310)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78245746..78255496)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene protein interacting with cyclin A1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:78029402-78029555 Neighboring gene SPT6, histone chaperone and transcription elongation factor Neighboring gene STARR-seq mESC enhancer starr_30092 Neighboring gene small nuclear ribonucleoprotein N pseudogene Neighboring gene bridge-like lipid transfer protein family member 2 Neighboring gene predicted gene 3948 Neighboring gene ribosomal protein S6 kinase related

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Bibliography

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Related articles in PubMed

  1. Stromal cell derived factor-2 (Sdf2): a novel protein expressed in mouse. Lorenzon-Ojea AR, et al. Int J Biochem Cell Biol, 2014 Aug. PMID 24878610
  2. Isolation and characterization of a novel secretory protein, stromal cell-derived factor-2 (SDF-2) using the signal sequence trap method. Hamada T, et al. Gene, 1996 Oct 17. PMID 8918255
  3. SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organs. Carramolino L, et al. Gene, 1997 Aug 22. PMID 9305759
  4. Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Shirozu M, et al. Genomics, 1996 Nov 1. PMID 8938438
  5. Cracking the egg: molecular dynamics and evolutionary aspects of the transition from the fully grown oocyte to embryo. Evsikov AV, et al. Genes Dev, 2006 Oct 1. PMID 17015433, Free PMC Article

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Endonuclease-mediated (1) 
  • Gene trapped (1) 

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Clone Names

  • MGC107120

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables misfolded protein binding IEA
Inferred from Electronic Annotation
more info
  
enables misfolded protein binding ISO
Inferred from Sequence Orthology
more info
  
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding IEA
Inferred from Electronic Annotation
more info
  
involved_in chaperone cofactor-dependent protein refolding ISO
Inferred from Sequence Orthology
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
  
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
  
part_of protein folding chaperone complex IEA
Inferred from Electronic Annotation
more info
  
part_of protein folding chaperone complex ISO
Inferred from Sequence Orthology
more info
  

General protein information

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Preferred Names
stromal cell-derived factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359106.2 → NP_001346035.2  stromal cell-derived factor 2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070

  2. NM_001404338.1 → NP_001391267.1  stromal cell-derived factor 2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070

  3. NM_001404339.1 → NP_001391268.1  stromal cell-derived factor 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL591070

  4. NM_001404340.1 → NP_001391269.1  stromal cell-derived factor 2 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070

  5. NM_001404341.1 → NP_001391270.1  stromal cell-derived factor 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL591070

  6. NM_001404342.1 → NP_001391271.1  stromal cell-derived factor 2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070

  7. NM_001404343.1 → NP_001391272.1  stromal cell-derived factor 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL591070
    Related
    ENSMUST00000154080.2

  8. NM_001404344.1 → NP_001391273.1  stromal cell-derived factor 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL591070

  9. NM_009143.4 → NP_033169.4  stromal cell-derived factor 2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
    Consensus CDS
    CCDS25096.2
    UniProtKB/Swiss-Prot
    P97307, Q9DCT5
    UniProtKB/TrEMBL
    Q6P5I1
    Related
    ENSMUSP00000002133.10, ENSMUST00000002133.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    78136817..78146310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9DCT5.1 GenPept UniProtKB/Swiss-Prot:Q9DCT5

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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