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Sdf2 stromal cell derived factor 2 [ Mus musculus (house mouse) ]

Gene ID: 20316, updated on 3-Apr-2024

Summary

Official Symbol
Sdf2provided by MGI
Official Full Name
stromal cell derived factor 2provided by MGI
Primary source
MGI:MGI:108019
See related
Ensembl:ENSMUSG00000002064 AllianceGenome:MGI:108019
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Mus musculus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary
Predicted to enable misfolded protein binding activity. Predicted to be involved in chaperone cofactor-dependent protein refolding. Predicted to be located in endoplasmic reticulum. Predicted to be part of chaperone complex. Orthologous to human SDF2 (stromal cell derived factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression
Ubiquitous expression in ovary adult (RPKM 68.0), genital fat pad adult (RPKM 59.3) and 28 other tissues See more
Orthologs
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Genomic context

See Sdf2 in Genome Data Viewer
Location:
11 B5; 11 46.74 cM
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (78136817..78146310)
108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (78245746..78255496)

Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene protein interacting with cyclin A1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:78029402-78029555 Neighboring gene SPT6, histone chaperone and transcription elongation factor Neighboring gene STARR-seq mESC enhancer starr_30092 Neighboring gene small nuclear ribonucleoprotein N pseudogene Neighboring gene bridge-like lipid transfer protein family member 2 Neighboring gene predicted gene 3948 Neighboring gene ribosomal protein S6 kinase related

Genomic regions, transcripts, and products

Expression

  • Project title: Mouse ENCODE transcriptome data
  • Description: RNA profiling data sets generated by the Mouse ENCODE project.
  • BioProject: PRJNA66167
  • Publication: PMID 25409824
  • Analysis date: n/a

Variation

Alleles

Alleles of this type are documented at Mouse Genome Informatics  (MGI)
  • Gene trapped (1) 
  • Endonuclease-mediated (1) 

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Clone Names

  • MGC107120

Gene Ontology Provided by MGI

Function Evidence Code Pubs
enables misfolded protein binding ISO
Inferred from Sequence Orthology
more info
 
Process Evidence Code Pubs
involved_in chaperone cofactor-dependent protein refolding ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
located_in endoplasmic reticulum ISO
Inferred from Sequence Orthology
more info
 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 
part_of protein folding chaperone complex ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
stromal cell-derived factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001359106.2NP_001346035.2  stromal cell-derived factor 2 isoform 2 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
  2. NM_001404338.1NP_001391267.1  stromal cell-derived factor 2 isoform 3 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
  3. NM_001404339.1NP_001391268.1  stromal cell-derived factor 2 isoform 4

    Status: VALIDATED

    Source sequence(s)
    AL591070
  4. NM_001404340.1NP_001391269.1  stromal cell-derived factor 2 isoform 5 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
  5. NM_001404341.1NP_001391270.1  stromal cell-derived factor 2 isoform 6

    Status: VALIDATED

    Source sequence(s)
    AL591070
  6. NM_001404342.1NP_001391271.1  stromal cell-derived factor 2 isoform 8 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
  7. NM_001404343.1NP_001391272.1  stromal cell-derived factor 2 isoform 7

    Status: VALIDATED

    Source sequence(s)
    AL591070
    Related
    ENSMUST00000154080.2
  8. NM_001404344.1NP_001391273.1  stromal cell-derived factor 2 isoform 9

    Status: VALIDATED

    Source sequence(s)
    AL591070
  9. NM_009143.4NP_033169.4  stromal cell-derived factor 2 isoform 1 precursor

    Status: VALIDATED

    Source sequence(s)
    AL591070
    Consensus CDS
    CCDS25096.2
    UniProtKB/Swiss-Prot
    P97307, Q9DCT5
    UniProtKB/TrEMBL
    Q6P5I1
    Related
    ENSMUSP00000002133.10, ENSMUST00000002133.9

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

  1. NC_000077.7 Reference GRCm39 C57BL/6J

    Range
    78136817..78146310
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)